39837-09-7

Basic information

• Product Name: N-(2-oxotetrahydro-3-thienyl)benzamide
• Synonyms: N-(2-oxotetrahydro-3-thienyl)benzamide;N-(2-oxotetrahydrothiophen-3-yl)benzamide
• CAS NO: 39837-09-7
• Molecular Formula: C₁₁H₁₁NO₂S
• Molecular Weight: 221.27554
• Mol File: 39837-09-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-oxotetrahydro-3-thienyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-oxotetrahydro-3-thienyl)benzamide(39837-09-7)
• EPA Substance Registry System: N-(2-oxotetrahydro-3-thienyl)benzamide(39837-09-7)

Safety Data

• Hazardous Substances Data: 39837-09-7(Hazardous Substances Data)

Upstream product

• 6038-19-3 3-aminodihydrothiophen-2(3H)-one hydrochloride 
• 98-88-4 benzoyl chloride 

Downstream Products

• 30577-53-8 Bis-α-N-benzoyl-DL-homocystin-dihydroxamsaeure 
• 10593-85-8 DL-homocysteine thiolactone 

Relevant articles and documents

Preparation Method for Homocystein Thiolactone or Selenolactone

The present invention provides an expensive reagent such as homocysteine thiolactone or selenolactone as the main intermediate of erdosteine, or an expensive reagent such as HI. More specifically, A) a homoserine lactone or N - protected homoserine is reacted with a thiocarboxylic acid metal salt or selenocarboxylic acid metal salt (RCOXM, X=S or Se). B) Step A) of producing homocysteine thiolactone or homocysteine sonoactone by deprotection of N - protected homocysteine thiolactone or N - protected homocysteine seleactone. The present invention relates to a method for producing homocysteine thiactone or homocysteine senolactone or a salt thereof by the following reaction scheme. [Reaction Scheme] Then, this time. X Is S or Se, R and R ' are independently alkyl or aryl which is C1 - C6, and M is Na or K.

Synthesis of S-linked carbohydrate analogues via a Ferrier reaction

In this work, the synthetic utility of the Ferrier reaction to access S-linked disaccharides and S-linked glycoamino acids has been probed. Significantly, entry to a range of 1,4- and 1,6-S-linked disaccharides has been achieved using glycals derived from glucose and galactose, and sulfur containing coupling partners derived from methyl α-d-glucopyranoside. Access to S-linked glycoamino acids and glycopeptides has also been achieved using protected cysteine and homocysteine coupling partners within the Ferrier reaction. Functionalisation of the Ferrier products, for example, via dihydroxylation using OsO4 or amino acid coupling, and deprotection of the targets have also been achieved. In this way, entry to materials of interest as mimics of biologically interesting disaccharides and glycopeptides has been realised, including targets derived from rare sugars such as talopyranose and gulopyranose.

Method of preparing ligands for hydrophobic interaction chromatography

The invention is a method of preparing multimodal ligands for hydrophobic interaction chromatography (HIC), which comprises providing a cyclic scaffold comprising a thiol, an amine and a carbonyl group; derivatisation of the nitrogen with a reagent to int