406478-96-4 Usage
Uses
Used in Chemical Research:
(S)-2-(2-PROPENYL)-2-CARBOXY-5-OXO-PYRROLIDINE is used as a research compound for studying its toxic effects and potential applications in the field of chemistry and pharmacology. Its unique properties as a neurotoxin make it a subject of interest for understanding the mechanisms of action and developing potential antidotes or treatments for poisoning.
Used in Forensic Science:
In forensic science, (S)-2-(2-PROPENYL)-2-CARBOXY-5-OXO-PYRROLIDINE is used as a toxicological marker in cases involving poisoning or suspicious deaths. Its detection can help identify the cause of death and provide crucial evidence in criminal investigations.
Used in Historical Context:
(S)-2-(2-PROPENYL)-2-CARBOXY-5-OXO-PYRROLIDINE has been historically used as a poison for executions and assassinations. Understanding its historical use can provide insights into the development of poisons and their role in human history.
Please note that due to the highly toxic nature of (S)-2-(2-PROPENYL)-2-CARBOXY-5-OXO-PYRROLIDINE, its use is strictly limited to controlled environments and professional settings, such as research laboratories and forensic science facilities. It is not intended for any other applications or uses outside of these contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 406478-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,6,4,7 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 406478-96:
(8*4)+(7*0)+(6*6)+(5*4)+(4*7)+(3*8)+(2*9)+(1*6)=164
164 % 10 = 4
So 406478-96-4 is a valid CAS Registry Number.
406478-96-4Relevant articles and documents
INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION
-
, (2020/02/23)
The present invention relates to Compounds of Formula (I): Formula (I) and pharmaceutically acceptable salts or prodrug thereof, wherein R1, R2, R3, Ra, Rb, A and B are as defined herein. The present invention also relates to compositions comprising at least one compound of Formula (I), and methods of using the compounds of Formula (I) for treating or preventing HIV infection in a subject.
Rapid diastereocontrolled synthesis of 2,2,5-trisubstituted pyrrolidines
Chandan, Nandkishkor,Moloney, Mark G.
scheme or table, p. 3664 - 3666 (2009/02/05)
2,2,5-Trisubstituted pyrrolidines are available from allylic pyroglutamates by Ireland-Claisen ester rearrangement followed by Eschenmoser sulfide contraction and reduction in a highly diastereoselective and efficient sequence. Some of the products from this sequence exhibit activity against S. aureus, but are much less active against E. coli. The Royal Society of Chemistry 2008.
Conformationally restricted TRH analogues: Constraining the pyroglutamate region
Simpson, Jill C.,Ho, Chris,Berkley Shands,Gershengorn, Marvin C.,Marshall, Garland R.,Moeller, Kevin D.
, p. 291 - 302 (2007/10/03)
A modified synthetic route has been developed so that the steric size of constraints added to the pyroglutamate region of TRH (pGluHisProNH2) can be varied. Both an analogue with a smaller ethylene bridge and a larger, more flexible propane bri
