4164-37-8

Basic information

• Product Name: N,N-DINITROPIPERAZINE
• Synonyms: 1,4-Dinitro-1,4-diazacyclohexane;1,4-dinitro-piperazin;1,4-Dinitropiperazine;1,4-Dinitro-piperazine;N,N-DINITROPIPERAZINE;Piperazine, 1,4-dinitro- (6CI,7CI,8CI,9CI)
• CAS NO: 4164-37-8
• Molecular Formula: C₄H₈N₄O₄
• Molecular Weight: 176.13
• EINECS: 224-010-1
• Product Categories: PIPERIDINE
• Mol File: 4164-37-8.mol

Chemical Properties

• Boiling Point: 492.2°Cat760mmHg
• Flash Point: 251.5°C
• Appearance: /
• Density: 1.53g/cm³
• Vapor Pressure: 2.37E-09mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: N,N-DINITROPIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DINITROPIPERAZINE(4164-37-8)
• EPA Substance Registry System: N,N-DINITROPIPERAZINE(4164-37-8)

Safety Data

• Hazardous Substances Data: 4164-37-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Manufacturing:
N,N-Dinitropiperazine is used as an intermediate in pharmaceutical manufacturing for the synthesis of nitrogen-based heterocycles, such as piperazine derivatives. Its reactivity and ability to form various compounds make it a valuable component in the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, N,N-Dinitropiperazine serves as a reagent for the production of a range of chemical compounds. Its unique properties allow for the creation of diverse molecules with potential applications in various industries.
Used in Synthesis of Nitrogen-Based Heterocycles:
N,N-Dinitropiperazine is used as a key component in the synthesis of nitrogen-based heterocycles, which are important in the development of new pharmaceuticals and other chemical products. Its role in this process highlights its versatility and importance in the field of chemistry.

InChI:InChI=1/C4H8N4O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H2

Upstream product

• 4164-39-0 N,N'-diformylpiperazine 
• 10308-78-8 piperazinium dinitrate 
• 18940-57-3 1,4-diacetylpiperazine 
• 212609-19-3 N-cyclopentyloxycarbonyl-N'-tozylpiperazine 
• 212609-18-2 N-isopropyloxycarbonyl-N'-tozylpiperazine 
• 2345-72-4 1,4-bis-(trimethylsilyl)-piperazine 
• 142-64-3 piperazine dihydrochloride 
• 7250-99-9 1,4-bis(phenylsulfonyl)piperazine 

Downstream Products

• 140-79-4 N,N'-dinitrosopiperazine 
• 107938-05-6 N-nitroso-N'-nitropiperazine 
• 74-90-8 hydrogen cyanide 
• 124-38-9 carbon dioxide 
• 201230-82-2 carbon monoxide 
• 110-85-0 piperazine 

Relevant articles and documents

The nitrolysis of N,N-dialkylcarboxamides in liquid carbon dioxide

A method for the synthesis of N,N-dialkylnitramines by the ninrolysis of N,N-dialkylcarboxamides with a mixture of N2O5 and 100% HNO3 in liquid carbon dioxide was developed.

Synthesis of N,N-dialkylnitramines from secondary ammonium nitrates in liquid or supercritical carbon dioxide

An efficient explosion-proof method was developed for the preparation of N,N-dialkylnitramines by treatment of dialkylammonium nitrates with a mixture of nitric acid and acetic anhydride in the presence of ZnCl2 in liduid or supercritical carbon dioxide.

Nitrolysis of urethanes derived from secondary alcohols as a new method for the synthesis of secondary N-nitroamines

The reactions of dialkylurethanes R12NCOOR (RO is the residue of a secondary but not a primary alcohol) with nitrating reagents leads to the formation of the corresponding secondary N-nitroamines R12NNO2.

Clean nitrations: Novel syntheses of nitramines and nitrate esters by nitrodesilylation reactions using dinitrogen pentoxide (N2O5)

In this novel nitration method dinitrogen pentoxide (N2O5) in an inert solvent is used as the nitrating agent, thereby removing the need for strong acids as the reaction medium. The N2O5 cleaves heteroatom-silicon bonds, in silylamines and silyl ethers respectively, to yield the desired energetic groupings (nitramines or nitrate esters respectively) without liberation of acids which would occur with conventional substrates (amines or alcohols). These nitrodesilylation reactions proceed cleanly and in good yield, and the scope of the reaction is illustrated by 29 examples, some of which produce high energy compounds, notably plasticisers and an energetic polymer precursor. These reactions are therefore potentially clean nitrations for the manufacture of energetic compounds which will minimise the impact of this activity on the environment in the future.