425394-36-1

Basic information

• Product Name: 5-CHLORO-4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYL-PYRIMIDINE
• Synonyms: 5-CHLORO-4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYL-PYRIMIDINE;5-Chloro-2-methyl-6-(trifluoromethyl)pyrimidin-4-ol
• CAS NO: 425394-36-1
• Molecular Formula: C6H4ClF3N2O
• Molecular Weight: 212.56
• Mol File: 425394-36-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-CHLORO-4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYL-PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYL-PYRIMIDINE(425394-36-1)
• EPA Substance Registry System: 5-CHLORO-4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYL-PYRIMIDINE(425394-36-1)

Safety Data

• Hazardous Substances Data: 425394-36-1(Hazardous Substances Data)

Upstream product

• 141-78-6 ethyl acetate 
• 363-58-6 ethyl 2-chloro-4,4,4-trifluoro-3-oxobutanoate 
• 124-42-5 acetamidine hydrochloride 

Downstream Products

• 425394-33-8 4,5-dichloro-2-methyl-6-trifluoromethylpyrimidine 

Relevant articles and documents

Design, synthesis, insecticidal, and acaricidal activities of novel pyrimidinamine derivatives containing a biphenyl ether

A series of original pyrimidinamine derivatives containing a biphenyl ether moiety were designed and synthesized. Their structures were confirmed by 1H NMR, MS, and elemental analyses. Their insecticidal activities against lepidopteran and hemiptera insects and acaricidal activities were tested. The results of bioassay demonstrated that 9k showed the best activity (LC50 = 2.08 mg/L) against Tetranychus urticae, which is comparable with the positive control, spirotetramat (LC50 = 2.27 mg/L), and 9g showed better activity (LC50 = 0.52 mg/L) against Aphis fabae than the positive control, imidacloprid (LC50 = 1.02 mg/L), and relatively good activity (LC50 = 2.49 mg/L) against T urticae. Their structure-activity relationships indicated that both an ethyl group on the 4-position of the pyrimidine ring and alkyl chain as a para-substituent group of the benzene ring showed good biological activity.

PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME

The present invention provides a pyrimidine derivative represented by the formula: wherein R1p and R1q are the same or different, and each represents (1)hydrogen, (2)halogen, (3) a C1-6alkyl group which may be substituted or (4) a C1-6alkoxy group, and so on, R2 is halogen, a C1-6alkyl group, cyano group, and so on, Ar is a phenyl group which may be substituted or is a condensed hetero ring which may be substituted, which has excellent selective herbicidal activity, and a herbicide containing the derivative.