363-58-6

Basic information

• Product Name: Ethyl 2-chloro-4,4,4-trifluoroacetoacetate
• Synonyms: ART-CHEM-BB B023057;ETHYL 2-CHLORO-3-KETO-4,4,4-TRIFLUOROBUTYRATE;ETHYL 2-CHLORO-4,4,4-TRIFLUORO-3-OXOBUTYRATE;ETHYL 2-CHLORO-4,4,4-TRIFLUOROACETATE;ETHYL 2-CHLORO-4,4,4-TRIFLUOROACETOACETATE;2-CHLORO-4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID ETHYL ESTER;AKOS B023057;Ethyl 2-chloro-4,4,4-trifluoroacetoacetate 95%
• CAS NO: 363-58-6
• Molecular Formula: C₆H₆ClF₃O₃
• Molecular Weight: 218.56
• EINECS: -0
• Mol File: 363-58-6.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 67 °C
• Flash Point: 28
• Appearance: /
• Density: 1.39
• Vapor Pressure: 1.19mmHg at 25°C
• Refractive Index: 1.388
• PKA: 4.96±0.35(Predicted)
• BRN: 1787023
• CAS DataBase Reference: Ethyl 2-chloro-4,4,4-trifluoroacetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-chloro-4,4,4-trifluoroacetoacetate(363-58-6)
• EPA Substance Registry System: Ethyl 2-chloro-4,4,4-trifluoroacetoacetate(363-58-6)

Safety Data

• Hazard Codes: F,Xi
• Statements: 34-36
• Safety Statements: 26-36/37/39
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 363-58-6(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Uses

Ethyl 2-Chloro-4,4,4-trifluoroacetoacetate is used in preparation of furoindazole derivatives as GPR84 antagonists useful in treating diseasess.

InChI:InChI=1/C6H6ClF3O3/c1-2-13-5(12)3(7)4(11)6(8,9)10/h3H,2H2,1H3/t3-/m1/s1

Upstream product

• 1522-43-6 ethyl 3-oxo-4,4,4-trifluorobutanoate enol 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 

Downstream Products

• 135026-17-4 ethyl 2-amino-4-(trifluoromethyl)oxazole-5-carboxylate 
• 78451-14-6 ethyl 2-chloro-4-trifluoromethyl-5-oxazolecarboxylate 
• 72850-52-3 ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate 
• 724426-32-8 2-(2,6-dichloro-4-trifluoromethyl-phenylamino)-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 724423-84-1 2-(2,4-dichloro-6-methyl-phenylamino)-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 724424-97-9 2-(2-bromo-4,6-dimethyl-phenylamino)-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 724426-20-4 2-(2-chloro-4,6-dimethyl-phenylamino)-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 724426-67-9 2-(2-bromo-4-isopropyl-phenylamino)-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 724426-63-5 2-(4-chloro-2,6-dimethyl-phenylamino)-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 724426-65-7 2-(2,4,6-tribromo-phenylamino)-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 724426-33-9 2-(2,6-dibromo-4-methyl-phenylamino)-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 344-72-9 ethyl 2-amino-4-(trifluoromethyl)-5-thiazole-carboxylate 
• 431-37-8 3-chloro-1,1,1-trifluoroacetone 
• 106203-24-1 4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

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Chalcone compound and applications thereof

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