4394-11-0Relevant articles and documents
Metal-free arylation of benzene and pyridine promoted by amino-linked nitrogen heterocyclic carbenes
Chen, Wen-Ching,Hsu, Yu-Chen,Shih, Wei-Chun,Lee, Ching-Yu,Chuang, Wen-Han,Tsai, Yi-Fang,Chen, Peter Ping-Yu,Ong, Tiow-Gan
supporting information; experimental part, p. 6702 - 6704 (2012/07/14)
An amino-linked nitrogen heterocyclic carbene (amino-NHC), 1-tBu, has been shown to mediate carbon-carbon coupling through the direct C-H functionalization of benzene and pyridine in the absence of a metal catalyst. Using EPR, the first spectroscopic evidence corroborating the single electron transfer mechanism for the metal-free carbon-carbon coupling manifold, as reported by others, is introduced.
Ligand-promoted C3-selective arylation of pyridines with Pd catalysts: Gram-scale synthesis of (±)-preclamol
Ye, Mengchun,Gao, Guo-Lin,Edmunds, Andrew J. F.,Worthington,Morris, James A.,Yu, Jin-Quan
supporting information; experimental part, p. 19090 - 19093 (2012/01/07)
The first example of Pd-catalyzed, C3-selective arylation of unprotected pyridines has been developed by employing a catalytic system consisting of Pd(OAc)2 and 1,10-phenanthroline. This protocol provides an expeditious route to an important class of 3-arylpyridines and 3-arylpiperidines frequently found in bioactive compounds. A brief synthesis of the drug molecule (±)-preclamol is also reported.
PREPARATION OF PYRIDYL GRIGNARD REAGENTS AND CROSS COUPLING REACTIONS WITH SULFOXIDES BEARING AZAHETEROCYCLES
Furukawa, Naomichi,Shibutani, Tadao,Fujihara, Hisashi
, p. 5845 - 5848 (2007/10/02)
Pyridyl Grignard reagents were prepared from the corresponding iodopyridine and EtMgBr.New cross coupling reactions of the Grignard reagents with azaheterocycles took place on the sulfinyl sulfur atom to afford biazaheteroaryls.
PHOTOCHEMICAL ARYLATION BY OXIME ESTERS IN BENZENE AND PYRIDINE: SIMPLE SYNTHESIS OF BIARYL COMPOUNDS
Hasebe, Masato,Kogawa, Koichi,Tsuchiya, Takashi
, p. 3887 - 3890 (2007/10/02)
Irradiation of benzophenone O-arenecarbonyloximes in benzene and pyridine affords the corresponding arylbenzenes and arylpyridines, respectively, in high yields.
