4471-41-4

Basic information

• Product Name: 1,4-bis[(2-hydroxyethyl)amino]anthraquinone
• Synonyms: 1,4-bis[(2-hydroxyethyl)amino]anthraquinone;1,4-bis(2-hydroxyethylamino)anthracene-9,10-dione;1,4-Bis[(2-hydroxyethyl)amino]-9,10-anthracenedione;1,4-Bis[(2-hydroxyethyl)amino]-9,10-anthraquinone;C.I.61545;C.I.Disperse Blue 23;1,4-Bis[(2-hydroxyethyl)amino]anthra-9,10-quinone;Acetoquinone Blue BF
• CAS NO: 4471-41-4
• Molecular Formula: C₁₈H₁₈N₂O₄
• Molecular Weight: 326.34652
• EINECS: 224-743-7
• Mol File: 4471-41-4.mol

Chemical Properties

• Melting Point: 248°C
• Boiling Point: 464.4°C (rough estimate)
• Flash Point: 350.4°C
• Appearance: /
• Density: 1.2825 (rough estimate)
• Vapor Pressure: 4.28E-18mmHg at 25°C
• Refractive Index: 1.5700 (estimate)
• Water Solubility: 783.3ug/L(25 oC)
• CAS DataBase Reference: 1,4-bis[(2-hydroxyethyl)amino]anthraquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis[(2-hydroxyethyl)amino]anthraquinone(4471-41-4)
• EPA Substance Registry System: 1,4-bis[(2-hydroxyethyl)amino]anthraquinone(4471-41-4)

Safety Data

• Hazardous Substances Data: 4471-41-4(Hazardous Substances Data)

Usage

Uses

Used in Textile Industry:
1,4-Bis[(2-hydroxyethyl)amino]anthraquinone is used as a dye for [textile materials] for [its bright blue color and fastness properties]. It provides a strong and long-lasting color to fabrics, making it suitable for various textile applications.
Used in Plastics Industry:
1,4-Bis[(2-hydroxyethyl)amino]anthraquinone is used as a colorant for [plastic materials] for [its ability to provide a vibrant blue color and resistance to fading]. It is ideal for use in the production of colored plastics that require a strong and durable color.
Used in Paints and Coatings Industry:
1,4-Bis[(2-hydroxyethyl)amino]anthraquinone is used as a pigment for [paints and coatings] for [its bright blue color and resistance to fading and staining]. It is suitable for use in various types of paints and coatings, providing a long-lasting and vibrant color.
Used in Inks Industry:
1,4-Bis[(2-hydroxyethyl)amino]anthraquinone is used as a colorant for [inks] for [its strong color properties and fastness to different conditions]. It is ideal for use in the production of high-quality inks for various printing applications.
Used in Cosmetics Industry:
1,4-Bis[(2-hydroxyethyl)amino]anthraquinone is used as a color additive for [cosmetics] for [its bright blue color and resistance to fading]. It is suitable for use in various cosmetic products, providing a vibrant and long-lasting color.

Preparation

1,4-Dihydroxyanthracene-9,10-dione or anthracene-1,4,9,10-tetraol?and 2-Aminoethanol condensation.

Standard(Polyamide)

Ironing Fastness

Fading

Stain

ISO

4-5

InChI:InChI=1/C18H18N2O4/c21-9-7-19-13-5-6-14(20-8-10-22)16-15(13)17(23)11-3-1-2-4-12(11)18(16)24/h1-6,19-22H,7-10H2

Upstream product

• 75-21-8 oxirane 
• 128-95-0 1,4-diamino-9,10-anthraquinone 
• 64-19-7 acetic acid 
• 98-95-3 nitrobenzene 
• 111271-34-2 N,N'-(9,10-dioxo-9,10-dihydro-anthracene-1,4-diyl)-bis-carbamic acid bis-(2-chloro-ethyl ester) 
• 81-64-1 1,4-dihydroxy-9,10-anthracenedione 
• 141-43-5 ethanolamine 
• 17648-03-2 9,10-Dihydroxy-2,3-dihydro-anthracene-1,4-dione 
• 5327-72-0 1,4-diamino-anthracene-9,10-diol 
• 28736-42-7 1,4-difluoroanthracene-9,10-dione 
• 27343-67-5 1,4-bis-<2-Hydroxy-aethylamino>-anthrahydrochinon 
• 40498-13-3 2,3-dihydro-1,4-dihydroxyanthraquinone 

Downstream Products

• 70477-04-2 1,4-bis<<2-(diethylamino)ethyl>amino>anthracene-9,10-dione 
• 64862-96-0 ametantrone 
• 3008-82-0 1,4-bis-(2-morpholin-4-yl-ethylamino)-anthraquinone 

Relevant articles and documents

Dyestuff, ink and electric wetting display device

The invention provides an organic dyestuff, ink and an electric wetting display device. Being different from extremely low solubility of a common dyestuff with a diamino substituted anthraquinone structure in a non-polar organic solvent, the dyestuff provided by the invention has very high solubility in the non-polar organic solvent, so that the dyestuff can be put into large-scale production. After the organic dyestuff is dissolved into the organic solvent, the ink applicable to electric wetting display, and the electric wetting display device applying the ink can be prepared.

Near-IR region absorbing 1,4-diaminoanthracene-9,10-dione motif?based?ratiometric chemosensors for Cu2+

1,4-Bis[2-aminoethylamino]anthracene-9,10-diones selectively bind with Cu2+ to form complexes with unusual selectivity under basic conditions. The deprotonation of the aryl amine NH in the case of these chemosensors causes a bathochromic shift in the absorption band from 585 nm and 635 nm to 725 nm and enables ratiometric estimation of Cu2+ between pH 8 and 12.

Synthesis and Antitumor Evaluations of Symmetrically and Unsymmetrically Substituted 1,4-Bisanthracene-9,10-diones and 1,4-Bis-5,8-dihydroxyanthracene-9,10-diones

The ipso bis displacements of fluoride from 1,4-difluoroanthracene-9,10-dione (3) and 1,4-difluoro-5,8-dihydroxyanthracene-9,10-dione (4) by excess of a diamine (or a monoamine) in pyridine at room temperature lead to the symmetrically substituted 1,4-bis-substituted analogues 5 and 6, respectively.The ipso monodisplacements of fluoride from 3 and 4 can be accomplished by treatment with less than 1 molar equiv of a diamine (or a monoamine) to yield 7 and 8, respectively.Treatment of 7 or 8 with a different diamine leads to the unsymmetrically substituted1,4-bisanthracene-9,10-diones 9 and 10, respectively.Many of the synthetic unsymmetrical analogues have been evaluated for their antitumor activity against L1210 in vitro and in vivo.Cross resistance of analogue 10a with mitoxantrone (2) and doxorubicin was evaluated against MDR lines in vitro against human colon carcinoma LOVO and its subline resistant to DOXO (LOVO/DOXO).Potential mechanisms for the observed cytotoxicity are presented and discussed.