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457641-02-0

C16H14N2O2S2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 457641-02-0 Structure

  • Basic information

    1. Product Name: C16H14N2O2S2
    2. Synonyms: C16H14N2O2S2
    3. CAS NO:457641-02-0
    4. Molecular Formula:
    5. Molecular Weight: 330.431
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 457641-02-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C16H14N2O2S2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C16H14N2O2S2(457641-02-0)
    11. EPA Substance Registry System: C16H14N2O2S2(457641-02-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 457641-02-0(Hazardous Substances Data)

457641-02-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 457641-02-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,7,6,4 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 457641-02:
(8*4)+(7*5)+(6*7)+(5*6)+(4*4)+(3*1)+(2*0)+(1*2)=160
160 % 10 = 0
So 457641-02-0 is a valid CAS Registry Number.

457641-02-0Relevant articles and documents

Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin- 4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2

Golub, Andriy G.,Bdzhola, Volodymyr G.,Briukhovetska, Nadiia V.,Balanda, Anatoliy O.,Kukharenko, Olexander P.,Kotey, Igor M.,Ostrynska, Olga V.,Yarmoluk, Sergiy M.

, p. 870 - 876 (2011/04/22)

A novel series of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids has been synthesized and tested in vitro towards human protein kinase CK2. It was revealed that the most active compounds inhibiting CK2 are 3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid and 3-{[5-(4-ethoxyphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid (IC 50 values are 0.1 μM and 0.125 μM, respectively). Structure-activity relationships of 28 tested thienopyrimidine derivatives have been studied and binding mode of this chemical class has been predicted. Evaluation of the inhibitors on seven protein kinases revealed considerable selectivity towards CK2.

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