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Hydrazinecarboxylic acid, 2-ethyl-, 1,1-dimethylethyl ester (9CI), also known as 2-ethylhydrazinecarboxylic acid, 1,1-dimethylethyl ester, is a colorless liquid chemical compound with the molecular formula C8H18N2O2 and a molecular weight of 174.24 g/mol. It is commonly used as a reagent in organic synthesis and as a building block in the production of pharmaceuticals and agrochemicals. Due to its potential hazards to human health and the environment, it should be handled with caution and in accordance with safety protocols.

476362-41-1

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476362-41-1 Usage

Uses

Used in Organic Synthesis:
Hydrazinecarboxylic acid, 2-ethyl-, 1,1-dimethylethyl ester (9CI) is used as a reagent in organic synthesis for the preparation of various chemical compounds. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, Hydrazinecarboxylic acid, 2-ethyl-, 1,1-dimethylethyl ester (9CI) is used as a building block for the production of various pharmaceuticals. Its ability to form stable intermediates and react with other compounds makes it a useful component in the development of new drugs and medications.
Used in Agrochemical Production:
Hydrazinecarboxylic acid, 2-ethyl-, 1,1-dimethylethyl ester (9CI) is also utilized in the agrochemical industry for the production of various agrochemicals. Its versatility in chemical reactions allows it to be incorporated into the synthesis of compounds used in agriculture, such as pesticides and herbicides, to improve crop yields and protect against pests.

Check Digit Verification of cas no

The CAS Registry Mumber 476362-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,6,3,6 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 476362-41:
(8*4)+(7*7)+(6*6)+(5*3)+(4*6)+(3*2)+(2*4)+(1*1)=171
171 % 10 = 1
So 476362-41-1 is a valid CAS Registry Number.

476362-41-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-(ethylamino)carbamate

1.2 Other means of identification

Product number -
Other names N'-ethylhydrazinecarboxylic acid tert-butyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:476362-41-1 SDS

476362-41-1Relevant articles and documents

USE OF CSE INHIBITORS FOR THE TREATMENT OF CUTANEOUS INJURIES OR CONDITIONS AND SLEEP-RELATED BREATHING DISORDERS

-

, (2014/02/16)

no abstract published

CYSTATHIONINE-Υ-LYASE (CSE) INHIBITORS

-

, (2014/02/16)

Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine -γ-lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.

Syntheses and antitumor activities of N′1, N′3-dialkyl-N′1,N′3-di- (alkylcarbonothioyl) malonohydrazide: The discovery of elesclomol

Chen, Shoujun,Sun, Lijun,Koya, Keizo,Tatsuta, Noriaki,Xia, Zhiqiang,Korbut, Timothy,Du, Zhenjian,Wu, Jim,Liang, Guiqing,Jiang, Jun,Ono, Mitsunori,Zhou, Dan,Sonderfan, Andrew

, p. 5070 - 5076 (2013/09/12)

A series of N′1,N′3-dialkyl- N′1,N′3-di(alkylcarbonothioyl) malonohydrazides have been designed and synthesized as anticancer agents by targeting oxidative stress and Hsp70 induction. Structure-activity relationship (SAR) studies lead to the discovery of STA-4783 (elesclomol), a novel small molecule that has been evaluated in a number of clinical trials as an anticancer agent in combination with Taxol.

N-Boc-O-tosyl hydroxylamine as a safe and efficient nitrogen source for the N-amination of aryl and alkyl amines: Electrophylic amination

Baburaj, Thankappan,Thambidurai, Sivalingam

experimental part, p. 1993 - 1996 (2011/10/08)

β-Boc-protected aryl and alkyl hydrazines, useful intermediates for azapeptides and N-substituted pyrazoles, were synthesized by electrophylic amination methodology, using less energetic N-Boc-O-tosyl hydroxylamine as an efficient nitrogen source. Also we have demonstrated a two-step, chromatography-free synthesis of N-Boc-O-tosyl hydroxylamine. Georg Thieme Verlag Stuttgart - New York.

Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists

Liu, Shilan,Liu, Yinhui,Wang, Hongmei,Ding, YiLi,Wu, Hao,Dong, Jingchao,Wong, Angela,Chen, Shu-Hui,Li, Ge,Chan, Manuel,Sawyer, Nicole,Gervais, Francois G.,Henault, Martin,Kargman, Stacia,Bedard, Leanne L.,Han, Yongxin,Friesen, Rick,Lobell, Robert B.,Stout, David M.

scheme or table, p. 5741 - 5745 (2010/04/30)

We describe herein a novel series of 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective inhibitors against the CXCR2 chemokine receptor and IL-8-mediated chemotaxis of a CXCR2-expressing cell line. Furthermore, these alkyl-hydrazine series inhibitors such as 5b demonstrated acceptable metabolic stability when incubated in human and rat microsomes.

Effective strategy for the systematic synthesis of hydrazine derivatives

Bredihhin, Aleksei,M?eorg, Uno

, p. 6788 - 6793 (2008/12/20)

A new and efficient strategy for the systematic synthesis of hydrazine derivatives is reported. It allows the synthesis of up to tetrasubstituted hydrazine derivatives with minimal number of steps using only one protecting group or without any of them at all. Simple and readily available starting materials such as hydrazine hydrate or phenylhydrazine can be used. A variety of substrates were used to investigate scope and limitations of this strategy, additionally one full synthetic sequence was performed.

Novel azapeptide inhibitors of hepatitis C virus serine protease

Bailey, Murray D.,Halmos, Ted,Goudreau, Nathalie,Lescop, Ewen,Llinàs-Brunet, Montse

, p. 3788 - 3799 (2007/10/03)

Azapeptides are known inhibitors of several serine and cysteine proteases. In seeking different classes of inhibitors for the HCV serine protease, a series of novel azapeptide-based inhibitors were investigated which incorporated noncleavable P1/P1′ aza-a

T-BUTOXYCARBONYLAMINOETHYLAMINE FOR THE SYNTHESIS OF PNA MONOMER UNITS, AMINO ACID DERIVATIVES, INTERMEDIATES THEREOF, AND PROCESSES FOR PRODUCTIONS OF THEM

-

, (2008/06/13)

A process for amino acid derivatives shown by the below general formula (I): (wherein R1 means a hydrogen atom or a straight chain or branched chain alkyl group with 1-5 carbon atoms.) having an object to provide a process of the amino acid derivatives of the formula I and their synthetic intermediate, t-butoxycarbonylamino-ethylamine, whereby it requires no tedious procedure and is also good in yield, and its application to a mass production is easy, and to provide novel amino acid derivatives of the formula IV, their synthetic intermediates, and a process thereof, characterized in that it comprises a step to obtain the amino acid derivatives shown by the general formula (I) by hydrolysis of compounds shown by the below formula (11):

Aza hydroxylated ethyl amine compounds utility

-

Page 68, (2010/02/06)

Disclosed are compounds of formula: and pharmaceutically acceptable salts and esters thereof, useful in treating and/or preventing Alzheimer's disease and other similar diseases, wherein RN, RC, R1, R2 and Rsub

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