503184-34-7 Usage
Uses
Used in Pharmaceutical Industry:
3-IODO-6-METHOXY-2-TRIFLUOROMETHYL-PYRIDINE is used as a synthetic intermediate for the development of biologically active compounds containing a trifluoromethyl moiety. The trifluoromethyl group is known to improve the pharmacokinetic properties of molecules, such as their lipophilicity, metabolic stability, and membrane permeability, which are crucial factors for drug efficacy and safety.
Used in Chemical Research:
In the field of chemical research, 3-IODO-6-METHOXY-2-TRIFLUOROMETHYL-PYRIDINE serves as a valuable building block for the synthesis of novel compounds with potential applications in various fields, including materials science, agrochemistry, and medicinal chemistry. Its unique structure allows for further functionalization and modification, enabling the creation of a diverse range of molecules with tailored properties and functions.
Used in the Synthesis of Fluorinated Compounds:
Fluorinated compounds have gained significant attention in recent years due to their unique chemical and biological properties. 3-IODO-6-METHOXY-2-TRIFLUOROMETHYL-PYRIDINE is used as a key starting material in the synthesis of fluorinated pyridine derivatives, which can be further modified to develop new molecules with improved biological activities and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 503184-34-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,1,8 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 503184-34:
(8*5)+(7*0)+(6*3)+(5*1)+(4*8)+(3*4)+(2*3)+(1*4)=117
117 % 10 = 7
So 503184-34-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H5F3INO/c1-13-5-3-2-4(11)6(12-5)7(8,9)10/h2-3H,1H3
503184-34-7Relevant articles and documents
COMPOUNDS AS CRF1 RECEPTOR ANTAGONISTS
-
Page 28, (2010/02/09)
The present invention relates to compounds of Formula I,or a stereoisomer thereof, a pharmaceutically acceptable salt thereof, or a prodrug thereof. The compounds of the inventions are CRF, receptor antagonists. Compounds of the invention are useful for t
CRF ligands via Suzuki and Negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine.
Arvanitis, Argyrios G,Arnold, Charles R,Fitzgerald, Lawrence W,Frietze, William E,Olson, Richard E,Gilligan, Paul J,Robertson, David W
, p. 289 - 291 (2007/10/03)
A series of imidazo[4,5-b]pyridines with a 7-(3-pyridyl) substituent is described as high affinity CRF receptor ligands. Individual analogues were synthesized from key intermediates obtained via palladium-catalyzed coupling of 3-pyridyl zinc or boronic acid organometallic intermediates with 2-benzyloxy-4-chloro-3-nitropyridine 12.
