52481-82-0

Basic information

• Product Name: 5,5-diphenyl-1,3-oxazolidin-2-one
• CAS NO: 52481-82-0
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.2692
• Mol File: 52481-82-0.mol

Chemical Properties

• Boiling Point: 467.2°C at 760 mmHg
• Flash Point: 236.4°C
• Density: 1.201g/cm³
• Vapor Pressure: 6.63E-09mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: 5,5-diphenyl-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-diphenyl-1,3-oxazolidin-2-one(52481-82-0)
• EPA Substance Registry System: 5,5-diphenyl-1,3-oxazolidin-2-one(52481-82-0)

Safety Data

• Hazardous Substances Data: 52481-82-0(Hazardous Substances Data)

Upstream product

• 88368-75-6 3,3-diphenyl-3-hydroxypropionic acid hydrazide 
• 4382-96-1 2-amino-1,1-diphenylethanol 
• 57-13-6 urea 
• 81467-24-5 3-(2-Hydroxy-2,2-diphenylethyl)-1,4,2-dioxazol-5-on 
• 119-61-9 benzophenone 
• 894-18-8 ethyl 3-hydroxy-3,3-diphenylpropanoate 
• 13961-05-2 1,1-diphenyl-1,3-propanediol 
• 67-56-1 methanol 
• 223906-31-8 tert-butyl (2-hydroxy-2,2-diphenylethyl)carbamate 
• 134668-33-0 2,2-Diphenyl-aziridine-1-carboxylic acid ethyl ester 

Downstream Products

• 223906-49-8 N-Propionyl-5,5-diphenyloxazolidin-2-one 
• 681035-21-2 (2-oxo-5,5-diphenyl-oxazolidin-3-yl)-phosphonic acid diethyl ester 
• 681035-22-3 (2-oxo-5,5-diphenyl-oxazolidin-3-yl)-phosphonic acid diphenyl ester 
• 107978-04-1 3-(1-oxo-3-phenylpropyl)-1,3-oxazolidin-2-one 

Relevant articles and documents

Trimethylphosphine-Promoted Alcoholysis of α,β-Unsaturated Imides and α,β-Unsaturated Esters

α,β-Unsaturated imides and α,β-unsaturated esters were found to undergo alcoholysis in the presence of trimethylphosphine. The reaction is initiated by nucleophilic addition of trimethylphosphine to the double bond of the α,β-unsaturated carbonyl compound. Saturated imides also undergo the alcoholysis in the presence of the corresponding α,β-unsaturated imide.

Synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols or 3-amino alcohols using iodobenzene dichloride and sodium azide

A general and efficient method for the synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols and 3-amino alcohols has been developed using the same reagent combination of iodobenzene dichloride (PhICl2) and sodium azide (NaN3).

N-Phosphoryl oxazolidinones as effective phosphorylating agents

A number of N-phosphoryl oxazolidinones have been prepared and evaluated, the best being 5,5-diphenyl oxazolidinones, the utility of which was demonstrated in the phosphorylation of a number of representative primary, secondary, tertiary, and phenolic alcohols.

Asymmetric alkylations using SuperQuat auxiliaries - An investigation into the synthesis and stability of enolates derived from 5,5-disubstituted oxazolidin-2-ones

Studies on the alkylation of enolates derived from a range of N-acyl-5,5-dimethyloxazolidin-2-ones and N-acyl-5,5-diphenyloxazolidin-2-ones reveal that high yields and high diastereoselectivities are best obtained when homochiral 4-isopropyl-5,5-dimethyloxazolidin-2-one is employed as a chiral auxiliary.

1,3-Oxazolidin-2-ones from 1H-Aziridines by a Novel Stratagem which Mimics the Direct Insertion of CO2

N-Ethoxycarbonylaziridines 2 undergo smooth thermal transformation into 1,3-oxazolidin-2-ones 3 on flash pyrolysis by a tandem reaction sequence equivalent to direct insertion of CO2 into the parent 1H-aziridine.

Cyclic Carbonylation of 3-Hydroxycarbohydroxamic Acids with 1,1'-Carbonyldiimidazole

The reaction of 3-hydroxycarbohydroxamic acids 3 with 1,1'-carbonyldiimidazole produces as a function of the substitution of 3 heterocycles of type 1, 4, and 5.In the presence of imidazole the 3-(2-hydroxyalkyl)-1,4,2-dioxazol-5-ones 1 undergo rearrangeme