- Preparation method of citral (by machine translation)
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A corresponding Grignard reagent or Witititg reagent is obtained by Grignard reaction or substitution reaction of halogenated acetaldehyde acetal or tripolyhalogenated acetaldehyde and reagent 1 (magnesium powder, triphenylphosphine or triphenyl phosphite), then the obtained Grignard reagent or Wititittig reagent is reacted with 6 - methyl -5 - heptene -2 - ketone, and then subjected to acidification and deprotection to obtain citral. The preparation method has the advantages of cheap and easily available raw materials, simple operation steps, safety, environmental protection, easiness in realization, high reaction atomic economy and selectivity, high yield and purity, low product cost and suitability for green industrial production. (by machine translation)
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Paragraph 0078; 0103-0106; 0109-0112
(2020/09/09)
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- COMPOUND ACTING AS ANTIBIOTICS
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The present invention provides a novel antibiotic compound represented by the following formula (I), a pharmaceutically acceptable salt thereof, an ester thereof, a prodrug thereof, a solvate thereof, or a deuterated analog thereof, or a stereoisomer thereof. The compound of the present invention exhibits excellent antibacterial activity, especially against Gram bacteria. wherein each group is defined as in the description.
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Paragraph 0174; 0176
(2020/12/22)
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- A selective colorimetric and ratiometric fluorescent probe for hydrogen sulfide
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A reaction-based colorimetric and ratiometric fluorescent probe based on an ICT-strategy for selective detection of H2S that exploited the H2S-mediated reduction of nitrocompound to amines was explored. And it displayed high selectivity for H2S over other relevant reactive sulfur, oxygen, nitrogen species and other anions with more than 120 nm blue shift and the change of emission intensity ratio inducted by H2S was over 4750.
- Wu, Ming-Yu,Li, Kun,Hou, Ji-Ting,Huang, Zheng,Yu, Xiao-Qi
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p. 8342 - 8347,6
(2012/12/12)
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- KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS
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The present invention provides ketolide derivatives, which can be used as anti-bacterial agents. Compounds disclosed herein can be used for the treating or preventing conditions caused by or contributed to by gram positive, gram negative or anaerobic bacteria, more particularly against, for example, Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp., Chlamydia spp., Mycoplasm, Legionella spp., Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillus, Enterobactericeae or any combination thereof. Also provided are processes for preparing compounds disclosed herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods of treating bacterial infections.
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Page/Page column 23
(2009/07/17)
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