5325-94-0

Basic information

• Product Name: ETHYL 1-PIPERIDINECARBOXYLATE
• Synonyms: 1-piperidinecarboxylicacid,ethylester;pentamethyleneurethane;ETHYL 1-PIPERIDINECARBOXYLATE;piperidine-1-carboxylic acid ethyl ester;1-Ethoxycarbonylpiperidine;N-(Ethoxycarbonyl)piperidine;N-Carbethoxypiperidine;NSC 100911
• CAS NO: 5325-94-0
• Molecular Formula: C₈H₁₅NO₂
• Molecular Weight: 157.21
• Product Categories: API intermediates;Building Blocks;Heterocyclic Building Blocks;Piperidines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 5325-94-0.mol

Chemical Properties

• Boiling Point: 183 °C(lit.)
• Flash Point: 187 °F
• Appearance: /
• Density: 1.018 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.127mmHg at 25°C
• Refractive Index: n20/D 1.459(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ETHYL 1-PIPERIDINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 1-PIPERIDINECARBOXYLATE(5325-94-0)
• EPA Substance Registry System: ETHYL 1-PIPERIDINECARBOXYLATE(5325-94-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: TM6300000
• Hazardous Substances Data: 5325-94-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research:
ETHYL 1-PIPERIDINECARBOXYLATE is used as a chemical compound in structure correlation studies for understanding its activity as a mosquito repellent. This application is significant for developing new and effective mosquito repellents to combat the spread of mosquito-borne diseases.
Used in Insect Repellent Development:
In the field of insect repellent development, ETHYL 1-PIPERIDINECARBOXYLATE is used as a key component in the research and development of new mosquito repellents. Its study contributes to the understanding of the compound's effectiveness in repelling mosquitoes, which can lead to the creation of more potent and long-lasting repellents to protect against mosquito-borne illnesses.

InChI:InChI=1/C8H15NO2/c1-2-11-8(10)9-6-4-3-5-7-9/h2-7H2,1H3

Upstream product

• 110-89-4 piperidine 
• 3741-66-0 Ethyl benzoyl carbonate 
• 3878-46-4 ethyl phenyl carbonate 
• 140410-40-8 3-allyloxycarbonyloxy-5-methoxyphenol 
• 541-41-3 chloroformic acid ethyl ester 
• 97463-22-4 1-[(Z)-2-nonenyl]piperidine 
• 98450-79-4 5,6,7,8-Tetrahydro-4-phenyl-8a-piperidino-4H,4aH-1-benzo-2-pyrancarbonsaeuremethylester 
• 124-38-9 carbon dioxide 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 626-67-5 N-methylcyclohexylamine 
• 125506-90-3 N,N-pentamethylene ethyl-2 (thienyl-2)-3 propene-2 amide 
• 125506-55-0 (piperidino carbamoyl)-1 propylphosphonate de diethyle 
• 125506-86-7 N,N-pentamethylene methyl-2 (chloro-4 phenyl)-3 propene-2 amide 
• 125506-87-8 N,N-pentamethylene methyl-2 (methoxy-4 phenyl)-3 propene-2 amide 
• 98225-21-9 cyclohexyl piperidine-1-carboxylate 
• 13939-69-0 piperidine carbamoyl chloride 
• 502-56-7 nonanone-5 
• 90-96-0 bis(p-methoxyphenyl)methanone 
• 19549-84-9 3-butyl ketone 
• 1018-97-9 2,2'-dimethylbenzophenone 
• 1868-00-4 3,3'-bis(trifluoromethyl)benzophenone 
• 1121-37-5 dicyclopropyl ketone 
• 22679-40-9 3,3’,5,5’-tetramethylbenzophenone 

Relevant articles and documents

Regioselective Preparation of Iodinated Phloroglucinols

A range of mono- and diiodinated phloroglucinols with differential protection of two hydroxy groups has been prepared. Key Words: Resorcinols, methoxy-, monoprotected / Iodination, mild / Iodobenzenes, electron-rich

Novel Synthesis of Carbamic Ester from Carbon Dioxide, Amine, and Ortho Ester

Carbon dioxide reacted with aliphatic amines and ortho esters to form carbamic esters in good yields.The influence of different ortho esters on the carbamate synthetic reaction is described.In the case of orthocarbonates, carbamic esters were obtained in high yields.The reaction of carbon dioxide, amines, and ortho esters may involve a competitive reaction between the esterification of carbamic acid produced by a reaction of carbon dioxide with amine, and the alkylation of amine.

Mild Reductive Cleavage of α-Aminoethers

1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinoline (1) is converted by ethyl chloroformate (ECF)/NaBH3CN to 2--4,5-dimethoxytoluene (4) via the quaternary urethane 2.The same procedure leads from laudanosine (5)

Alkenyl-copper derivatives. 28 (1) : Stereospecific synthesis of tertiary allylic amines of E and Z configuration

Aminoethers and aminothioethers react smoothly with organocopper and cuprate reagents to afford tertiary amines.The use of Z alkenyl cuprates or E alkenyl aluminium derivatives leads to Z or E tertiary allylic amines.Polysubstituted and variously functionalized alkenyl copper reagents react in the same way, and a straightforward synthesis of pure N,N-diethylnerylamine is described.The stereoisomeric purity of these allylic amines is in the 99.5-99.9percent range, and their conversion to the corresponding allylic chlorides is not accompanied by any stereochemical scrambling.