19549-84-9Relevant articles and documents
Application of catalytic dynamic resolution of N-Boc-2-lithiopiperidine to the asymmetric synthesis of 2-aryl and 2-vinyl piperidines
Beng, Timothy K.,Gawley, Robert E.
supporting information; experimental part, p. 394 - 397 (2011/04/12)
The highly enantioselective synthesis of 2-aryl-and 2-vinyl-piperidines has been accomplished through a catalytic dynamic resolution (CDR) of N-Boc-2-lithiopiperidine. The method has been applied to the synthesis of both enantiomers of the tobacco alkaloid anabasine.
N-CARBOETHOXYPIPERIDINE, A CONVENIENT REAGENT FOR THE PREPARATION OF SYMMETRICAL KETONES FROM ORGANOLITHIUMS
Prakash, G. K. Surya,York, Chentao,Liao, Qimu,Kotian, Kirtivan,Olah, George A.
, p. 79 - 84 (2007/10/02)
N-Carboethoxypiperidine on reaction with organolithium reagents, RLi, followed by acidic work-up gave excellent yields of the corresponding symmetrical ketones, R2CO.
α-Methylation of ketones via manganese-enolates: Absence of undesired polyalkylation
Reetz, Manfred T.,Haning, Helmut
, p. 7395 - 7398 (2007/10/02)
The transmetalation of ketone lithium-enolates using MnBr2 generates manganese-enolates which react with CH3I to provide α-methylated ketones with essentially no undesired polyalkylated byproducts.