54704-34-6

Basic information

• Product Name: 2-AMINO-3-CYCLOHEXYLPROPANE
• Synonyms: 2-AMINO-3-CYCLOHEXYLPROPANE;1-cyclohexylpropan-2-amine;L-1-methyl-2-cyclohexylethylamine
• CAS NO: 54704-34-6
• Molecular Formula: C₉H₁₉N
• Molecular Weight: 141.25
• Mol File: 54704-34-6.mol

Chemical Properties

• Boiling Point: 181.5°C at 760 mmHg
• Flash Point: 58.3°C
• Appearance: /
• Density: 0.858g/cm³
• Vapor Pressure: 0.848mmHg at 25°C
• Refractive Index: 1.46
• CAS DataBase Reference: 2-AMINO-3-CYCLOHEXYLPROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-3-CYCLOHEXYLPROPANE(54704-34-6)
• EPA Substance Registry System: 2-AMINO-3-CYCLOHEXYLPROPANE(54704-34-6)

Safety Data

• Hazardous Substances Data: 54704-34-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-AMINO-3-CYCLOHEXYLPROPANE is used as a building block in organic synthesis for the production of a wide range of organic compounds. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-AMINO-3-CYCLOHEXYLPROPANE is utilized as a key component in the development of new drugs and pharmaceutical products. Its potential applications in medicinal chemistry stem from its ability to be incorporated into drug molecules, potentially enhancing their efficacy and selectivity.
Used in Medicinal Chemistry:
2-AMINO-3-CYCLOHEXYLPROPANE is employed in medicinal chemistry for the design and synthesis of novel drug candidates. Its structural features can be leveraged to improve the pharmacokinetic and pharmacodynamic properties of drug molecules, contributing to the advancement of therapeutic agents.
Used in Specialty Chemicals Production:
2-AMINO-3-CYCLOHEXYLPROPANE may also find applications in the industrial production of specialty chemicals. Its unique chemical properties can be harnessed to create specialized compounds used in various industries, such as coatings, adhesives, and polymers.
Used as a Reagent in Chemical Processes:
In addition to its role as a building block, 2-AMINO-3-CYCLOHEXYLPROPANE can be used as a reagent in various chemical processes. Its reactivity and functional groups make it suitable for use in a range of chemical transformations, facilitating the synthesis of target compounds in research and industrial settings.

InChI:InChI=1/C9H19N/c1-8(10)7-9-5-3-2-4-6-9/h8-9H,2-7,10H2,1H3

Upstream product

• 768-50-3 1-cyclohexenylacetone 
• 60-15-1 2-amino-1-phenylpropane 
• 17322-34-8 (2-nitropropyl)benzene 
• 103-78-6 4-cyclohexyl-butan-2-one 
• 2043-61-0 cyclohexanecarbaldehyde 
• 26226-49-3 1-methyl-2-cyclohexyl nitroethylene 
• 17019-26-0 (E)-2-(hydroxyimino)-1-phenylpropan-1-one 

Downstream Products

• 1351781-84-4 C₁₂H₂₃NO₂ 
• 5913-12-2 (S)-(+)-1-cyclohexyl-2-propanamine 
• 52617-05-7 (R)-(-)-1-cyclohexyl-2-propanamine 

Relevant articles and documents

Enzymatic enantiomeric resolution of phenylethylamines structurally related to amphetamine

Both enantiomers of several phenylethylamines, structurally related to amphetamine, have been prepared in good yields and excellent enantiomeric purity by enzymatic kinetic resolution using CAL-B and ethyl methoxyacetate as the acyl donor. In the case of the 4-hydroxyderivative of amphetamine (compound 4i), the S enantiomer racemized possibly in a dynamic kinetic resolution (DKR) under the enzymatic conditions used. The Royal Society of Chemistry 2011.

HOMOGENEOUS HYDROGENATION OF NITROALIPHATIC COMPOUNDS CATALYZED BY GROUP VIII TRANSITION METAL PHOSPHINE COMPLEXES

A variety of Group VIII transition metal phosphine complexes were shown to be active catalysts for hydrogenation of nitroaliphatic compounds.The catalysis was determined to be homogeneous based on results of selective catalyst poisoning experiments using dibenzocyclooctatetraene and Hg.A deuterium labeling study showed that in the absence of added base the primary hydrogenation pathway does not involve intermediates containing C=N bonds.

Preparation of esters of phosphorus acids

Esters of phosphorus acids are prepared by an improved process whereby aromatic alcohols and phosphorus halides are reacted at specified temperatures in the presence of amine catalysts thereby providing high yields of substantially pure esters and allowing preparation of selected halogen-containing mono- and di-esters of phosphorus acids wherein halogen is directly bonded to phosphorus having substantially no side reactant contamination. The phosphorus esters are useful as intermediates in the preparation of plasticizers, oil additives and functional fluids.