17019-26-0

Basic information

• Product Name: 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)-
• CAS NO: 17019-26-0
• Molecular Formula: C9H9NO2
• Molecular Weight: 163.176
• Mol File: 17019-26-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)-(17019-26-0)
• EPA Substance Registry System: 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)-(17019-26-0)

Safety Data

• Hazardous Substances Data: 17019-26-0(Hazardous Substances Data)

Usage

General Description

1,2-Propanedione, 1-phenyl-, 2-oxime, (E)- is a chemical compound also known as 2-Phenyl-2-propanone oxime, which is a colorless to light yellow liquid at room temperature. It is used as a chemical intermediate in the production of various pharmaceuticals, agrochemicals, and fragrances. It is also commonly used as a reagent in organic synthesis and as a chelating agent in coordination chemistry. 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)- has potential applications in the fields of medicine, agriculture, and fragrance manufacturing, and its versatile properties make it a valuable addition to various chemical processes.

Upstream product

• 17019-18-0 anti-methylphenylglyoxime 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 7664-93-9 sulfuric acid 
• 14897-67-7 2-nitropropiophenone 
• 29024-92-8 1-hydroximino-1-phenylacetone 
• 25388-20-9 3-methyl-4-phenylisoxazole 
• 28867-78-9 (Z)-1-phenyl-1,2-propanedione 2-oxime 
• 93-55-0 1-phenyl-propan-1-one 
• 110-46-3 isopentyl nitrite 

Downstream Products

• 14838-15-4 u-2-amino-1-phenylpropan-1-ol 
• 60-15-1 2-amino-1-phenylpropane 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 5265-18-9 (+/-)-cathinone 
• 4937-86-4 1-phenyl-1,2-propanedione dioxime 
• 17019-18-0 anti-methylphenylglyoxime 
• 143677-98-9 5-methyl-2,2,4-triphenyl-2H-imidazole N-oxide 
• 61487-86-3 C₁₉H₁₈N₂O₅ 
• 2549-30-6 4-Methyl-2,5-diphenyloxazole N-oxide 
• 59489-36-0 2-amino-6-methyl-5-phenylpyrazine 
• 492-41-1 (1R,2S)-norephedrine 
• 37577-07-4 Norpseudoephedrine 
• 40421-52-1 (1R,2S)-1-phenylpropane-1,2-diol 
• 196409-10-6 (-)-(R)-1-hydroxy-1-phenyl-2-propanone 2-(O-methyloxime) 

Relevant articles and documents

Visible-Light-Induced Transition-Metal-Free Nitrogen-Centered Radical Strategy for the Synthesis of 2-Acylated 9 H-Pyrrolo[1,2- a]indoles

A convenient and efficient visible-light-induced tandem acylation/cyclization of N-propargylindoles with aryl- or alkyl-substituted acyl oxime esters for the synthesis of 2-acyl-substituted 9H-pyrrolo[1,2-a]indoles under transition-metal-free conditions, which proceeds via nitrogen-centered radical-mediated cleavage of the C-C σ-bond in acyl oxime esters, is established. The aryl or alkyl acyl radicals, which come from acyl oxime esters, attack the C-C triple bonds in N-propargylindoles and then go through intramolecular cyclization/isomerization.

Nitrosocarbonyl-Henry and Denitration Cascade: Synthesis of α-Ketoamides and α-Keto Oximes

An unprecedented Henry reaction of in situ generated nitrosocarbonyl intermediates and concomitant denitration cascade has been developed. The reaction is catalyzed by organic base at room temperature offering α-ketoamides, a demanding scaffold for drug discovery, in high yields. An alteration of substitution pattern also produced α-keto oximes, a high-value synthon. The protocol features operational simplicity and broad substrate scope.

Beckmann rearrangement of α-oximinoketones

The Beckmann rearrangement of α-oximinoketones gives benzoic acids as chief isolable products. Both first order and second order Beckmann rearrangements have been observed. The occurrence of first order Beckmann rearrangement in these oximinocarbonyl compounds is confirmed through the identification of the products obtained.