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4-(4-chlorophenoxy)-3,5-difluoroaniline is a chemical compound with the molecular formula C12H8 ClF2N O. It is an aniline derivative featuring a 4-chlorophenoxy group and two fluoro substituents on the benzene ring, known for its applications in the synthesis of pharmaceuticals, agrochemicals, dyes, and pigments, as well as for its insecticidal properties in agriculture.

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  • 549547-33-3 Structure
  • Basic information

    1. Product Name: 4-(4-chlorophenoxy)-3,5-difluoroaniline
    2. Synonyms: Benzenamine, 4-(4-chlorophenoxy)-3,5-difluoro-
    3. CAS NO:549547-33-3
    4. Molecular Formula: C12H8ClF2NO
    5. Molecular Weight: 255.6478264
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 549547-33-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 309.3±42.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.399±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 2.57±0.10(Predicted)
    10. CAS DataBase Reference: 4-(4-chlorophenoxy)-3,5-difluoroaniline(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-(4-chlorophenoxy)-3,5-difluoroaniline(549547-33-3)
    12. EPA Substance Registry System: 4-(4-chlorophenoxy)-3,5-difluoroaniline(549547-33-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 549547-33-3(Hazardous Substances Data)

549547-33-3 Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
4-(4-chlorophenoxy)-3,5-difluoroaniline is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides due to its unique chemical structure and properties.
Used in Dye and Pigment Production:
In the dye and pigment industry, 4-(4-chlorophenoxy)-3,5-difluoroaniline is utilized as a precursor for the production of dyes and pigments, offering a range of color options and enhancing the performance of these products.
Used as an Insecticide in Agriculture:
4-(4-chlorophenoxy)-3,5-difluoroaniline is employed as an insecticide in the agricultural industry, providing effective pest control and protecting crops from insect damage. Its insecticidal properties make it a valuable tool in maintaining crop yields and quality.
However, due to potential environmental and health hazards associated with 4-(4-chlorophenoxy)-3,5-difluoroaniline, strict regulations and safety precautions are necessary in its handling and use to minimize risks and ensure sustainable practices.

Check Digit Verification of cas no

The CAS Registry Mumber 549547-33-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,9,5,4 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 549547-33:
(8*5)+(7*4)+(6*9)+(5*5)+(4*4)+(3*7)+(2*3)+(1*3)=193
193 % 10 = 3
So 549547-33-3 is a valid CAS Registry Number.

549547-33-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(4-Chlorophenoxy)-3,5-difluoroaniline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:549547-33-3 SDS

549547-33-3Downstream Products

549547-33-3Relevant articles and documents

Methods of Treating Aneurysmal Dilatation, Blood Vessel Wall Weakness and Specifically Abdominal Aortic and Thoracic Aneurysm Using Matrix Metalloprotease-2 Inhibitors

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, (2011/04/24)

The present invention provides methods of treating aneurysmal dilatation, blood vessel wall weakness, and specifically abdominal aortic aneurysm and thoracic aneurysm by inhibiting MMPs and ADAM-10. Such compounds are useful in the in vitro study of the r

HUMAN ADAM-10 INHIBITORS

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Page 44, (2008/06/13)

The present invention provides compounds useful for inhibiting the ADAM-10 protein, with selectivity versus MMP-1. Such compounds are useful in the in vitro study of the role of ADAM-10 (and its inhibition) in biological processes. The present invention also comprises pharmaceutical compositions comprising one or more ADAM-10 inhibitors according to the invention in combination with a pharmaceutically acceptable carrier. Such compositions are useful for the treatment of cancer, arthritis, and diseases related to angiogenesis. Correspondingly, the invention also comprises methods of treating forms of cancer, arthritis, and diseases related to angiogenesis in which ADAM-10 plays a critical role.

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