572923-17-2

Basic information

• Product Name: (S)-4-(2-OXO-4-PHENYLOXAZOLIDIN-3-YL)-N-PROPYLBENZAMIDE
• Synonyms: (S)-4-(2-OXO-4-PHENYLOXAZOLIDIN-3-YL)-N-PROPYLBENZAMIDE
• CAS NO: 572923-17-2
• Molecular Formula: C₁₉H₂₀N₂O₃
• Molecular Weight: 324.37
• Product Categories: pharmacetical
• Mol File: 572923-17-2.mol

Chemical Properties

• Boiling Point: 528.369°C at 760 mmHg
• Flash Point: 273.348°C
• Appearance: /
• Density: 1.206g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• PKA: 15.16±0.46(Predicted)
• CAS DataBase Reference: (S)-4-(2-OXO-4-PHENYLOXAZOLIDIN-3-YL)-N-PROPYLBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(2-OXO-4-PHENYLOXAZOLIDIN-3-YL)-N-PROPYLBENZAMIDE(572923-17-2)
• EPA Substance Registry System: (S)-4-(2-OXO-4-PHENYLOXAZOLIDIN-3-YL)-N-PROPYLBENZAMIDE(572923-17-2)

Safety Data

• Hazardous Substances Data: 572923-17-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-4-(2-OXO-4-PHENYLOXAZOLIDIN-3-YL)-N-PROPYLBENZAMIDE is used as a potential pharmaceutical compound for its unique structure and functional groups. (S)-4-(2-OXO-4-PHENYLOXAZOLIDIN-3-YL)-N-PROPYLBENZAMIDE's chirality and specific stereochemistry may offer advantages in drug development, targeting specific biological pathways or receptors.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (S)-4-(2-OXO-4-PHENYLOXAZOLIDIN-3-YL)-N-PROPYLBENZAMIDE is utilized as a compound with potential therapeutic applications. Its structural features may allow for the development of new drugs with improved efficacy, selectivity, and reduced side effects.

InChI:InChI=1/C19H20N2O3/c1-2-12-20-18(22)15-8-10-16(11-9-15)21-17(13-24-19(21)23)14-6-4-3-5-7-14/h3-11,17H,2,12-13H2,1H3,(H,20,22)/t17-/m1/s1

Upstream product

• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 
• 223557-19-5 4-bromo-N-(propyl)benzamide 
• 39887-30-4 4-iodo-N-propyl-benzamide 
• 7461-32-7 4-chloro-N-n-propylbenzamide 

Downstream Products

• 876747-69-2 4-(2,2-dioxo-4-phenyl-1,2,3-oxathiazolidin-3-yl)-N-(propyl)benzamide 
• 876747-67-0 4-(2-oxo-4-phenyl-1,2,3-oxathiazolidin-3-yl)-N-(propyl)benzamide 
• 876747-64-7 4-(2-hydroxy-1-phenylethylamino)-N-(propyl)benzamide 

Relevant articles and documents

Cu-catalyzed N-arylation of oxazolidinones: An efficient synthesis of the κ-opioid receptor agonist CJ-15161

An efficient method for intermolecular N-arylation of oxazolidinones using catalytic copper in the presence of a bidentate ligand is reported. The conditions allow the use of copper and can be used to prepare enantiopure N-aryl β-amino alcohols. A short,

Palladium-catalyzed synthesis of N-aryloxazolidinones from aryl chlorides

(Matrix presented) An efficient method for intermolecular N-arylation of oxazolidinones using Pd2dba3 and various phosphine ligands in the presence of a weak base is reported. The conditions allow the use of cheaper aryl chlorides containing functionalities such as enolizable ketones, amides, etc., which would be incompatible with other coupling methods. The coupling reaction can be used to prepare enantiopure N-aryl β-amino alcohols. Depending on the stereoelectronic nature of the aryl chloride, careful choice of ligand was necessary for the success of these reactions.