608537-49-1Relevant articles and documents
CYCLOPROPYL ETHYLENE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME
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Paragraph 0339-0342; 0344, (2021/02/05)
The present invention provides a compound that have excellent harmful arthropod controlling effects, the compounds being represented by formula (I) [wherein R1 represents a hydrogen atom etc., and R21, R22, R31
ARYLAMIDES AND METHODS OF USE THEREOF
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Page/Page column 59, (2021/06/11)
The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.
INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS
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Page/Page column 423; 424, (2021/01/29)
The present invention is directed to indazole and azaindazole compounds which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.
SUBSTITUTED 2-AMINO-PYRAZOLYL-[1,2,4]TRIAZOLO[1,5A] PYRIDINE DERIVATIVES AND USE THEREOF
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, (2020/10/27)
Provided herein are 2-amino-pyrazolyl-[ 1,2,4]triazolo [1,5a]pyridine derivatives. Such compounds are useful, for example, for the treatment and/or prevention of neurodegenerative diseases or disorders such as ophthalmological neurodegenerative disorders. This disclosure also features compositions containing the same as well as methods of using and making the same.
PYRROLOPYRIMIDINE ITK INHIBITORS
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Paragraph 0447; 0448; 0449, (2020/02/27)
Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structures of Formulas (I)-(IV): wherein the R groups, m, n, and X are as defined in the detailed description. Methods of inhibition of ITK activity in a human or animal subject are also provided.
[...] compound pest control method (by machine translation)
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Paragraph 0248-0250, (2020/01/02)
[A] a method for controlling harmful organisms. (I) formula [a][In the formula, R1 The, represents a hydrogen atom or the like, R21 , R22 , R31 , And R32 The, same or different, represents a hydrogen
BICYCLIC COMPOUNDS FOR USE AS RIP1 KINASE INHIBITORS
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Page/Page column 132, (2019/05/07)
The invention provides novel compounds having the general formula (I) or pharmaceutically acceptable salts thereof, wherein RA, RB1, RB2, the A ring and the B ring are as described herein, pharmaceutical compositions inclu
PYRAZOLE PYRIMIDINE DERIVATIVE AND USES THEREOF
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Page/Page column 64-65, (2017/02/28)
The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or lnterleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
CARBOCYCLIC- AND HETEROCYCLIC-SUBSTITUTED HEXAHYDROPYRANO[3,4-d][1,3]THIAZIN-2-AMINE COMPOUNDS
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Page/Page column 70; 71, (2014/07/08)
The present invention provides compounds of formula (I), wherein the variables R1, R2, R5 and b are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, an
Rhodium-Catalyzed Asymmetric [5+2] Cycloaddition of Alkyne- Vinylcyclopropanes
Shintani, Ryo,Nakatsu, Hiroki,Takatsu, Keishi,Hayashi, Tamio
supporting information; experimental part, p. 8692 - 8694 (2010/03/24)
The development of such an asymmetric catalysis by the use of a rhodium complex coordinated with chiral phosphoramidite ligand, achieving very high enantiomeric excesses has been reported. Transition-metal-catalyzed cycloaddition of vinylcyclopropanes wit
