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2-butanone semicarbazone is a chemical compound derived from 2-butanone, also known as methyl ethyl ketone (MEK), and semicarbazide. It is formed through a reaction between 2-butanone and semicarbazide, resulting in a derivative that is often used in analytical chemistry for the detection and determination of aldehydes and ketones. The compound has the molecular formula C5H11N3O and is characterized by its ability to form a colored complex with aldehydes, which can be used for quantitative analysis. This property makes 2-butanone semicarbazone a valuable reagent in various chemical and pharmaceutical applications, particularly in the identification and quantification of carbonyl compounds in complex mixtures.

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  • 624-46-4 Structure
  • Basic information

    1. Product Name: 2-butanone semicarbazone
    2. Synonyms: 2-butanone semicarbazone;1-(1-Methylpropylidene)semicarbazide;1-sec-Butylidenesemicarbazide
    3. CAS NO:624-46-4
    4. Molecular Formula: C5H11N3O
    5. Molecular Weight: 129.19
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 624-46-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 239.23°C (rough estimate)
    3. Flash Point: °C
    4. Appearance: /
    5. Density: 1.1508 (rough estimate)
    6. Refractive Index: 1.5070 (estimate)
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-butanone semicarbazone(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-butanone semicarbazone(624-46-4)
    11. EPA Substance Registry System: 2-butanone semicarbazone(624-46-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 624-46-4(Hazardous Substances Data)

624-46-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 624-46-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 4 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 624-46:
(5*6)+(4*2)+(3*4)+(2*4)+(1*6)=64
64 % 10 = 4
So 624-46-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H11N3O/c1-3-4(2)7-8-5(6)9/h3H2,1-2H3,(H3,6,8,9)/b7-4+

624-46-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name METHYL ETHYL KETONE SEMICARBAZONE

1.2 Other means of identification

Product number -
Other names 2-butanone semicarbazone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:624-46-4 SDS

624-46-4Relevant articles and documents

1,2,3-Selenadiazole-driven single family MSNCs of CdSe

Jadhav, Aditi A.,Khanna, Pawan K.

, p. 14713 - 14722 (2017/11/28)

Herein, 1,2,3-selenadiazoles were instantly prepared by hand grinding the reactants via a solventless process and tested for their ability to act as a source of selenium for the synthesis of CdSe magic-sized nanoclusters (MSNCs) with size below 2 nm. The

Cyclization of the semicarbazones to 1,3,4-oxadiazole derivatives using ceric ammonium nitrate as oxidant

Vahedi,Lari,Bavand,Ameri

experimental part, p. 288 - 290 (2012/08/08)

Cyclization of the semicarbazones to 1,3,4-oxadiazole using ceric ammonium nitrate as oxidant was studied. 2-Imino-1,3,4-oxadiazolines can be produced from semicarbazones, which undergo thermolysis to amides. Benzoic acid benzylidene hydrazide can also be cyclized to 2-methoxy-2-phenyl-1,3,4-oxadiazole in the presence of ceric ammonium nitrate and methanol.

PYRAZOLOSPIROKETONE ACETYL-C0A CARBOXYLASE INHIBITORS

-

Page/Page column 38, (2009/12/27)

The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of acetyl-CoA carboxylase enzyme(s) in an animal.

Reactions of diazoalkanes with isocyanates. Synthesis of imidazolidine-2,4-diones, oxindoles, and oxazolidinones

Fulton, Janet B.,Warkentin, John

, p. 1177 - 1184 (2007/10/02)

Thermolysis of a 5,5-dialkyl-Δ3-1,3,4-oxadiazolin-2-one in nitrobenzene containing an aryl isocyanate at 150 deg C affords a 1,3-diaryl-5,5-dialkyl imidazolidine-2,4-dione, an N-arylcarbamoyl-3,3-dialkyloxindole, and a 3-aryl-2-arylimino-5,5-dialkyl-1,3-oxazolidin-4-one.Those products arise from attack of a diazoalkane, generated in situ from the oxadiazolinone by thermal cycloreversion, on the isocyanate function.Two imidazolidine diones, three oxazolidinones, and 14 oxindoles were prepared.

MULTINUCLEAR MAGNETIC RESONANCE AND RELATED STUDIES ON AZOMETHINE BORON COMPLEXES OF SEMICARBAZONES AND THIOSEMICARBAZONES

Bhal, L.,Singh, R. V.,Tandon, J. P.

, p. 251 - 260 (2007/10/02)

Synthetic and stereochemical features of some interesting boron complexes have been described.These three and four coordinated complexes have been prepared by the interaction of 2-isopropoxy-1, 3,2-benzodioxaborole with semicarbazones and thiosemicarbazones having the donor sets NOH and NSH in unimolar ratio and with semicarbazones and thiosemicarbazones having the donor sets HONOH and OHNSH in 1:1 and 2:1 molar ratios.Depending on the stoichiometry of the reactions, different moles of isopropanol are liberated and a variety of new boron azomethine complexes are obtained.On the basis of IR, (1)H NMR, (11)B NMR and (13)C NMR data plausible geometries have been proposed for the resulting derivatives, X-ray powder diffraction studies of a representative compound have also been carried out and the results show that adopts 'orthorhombic' type of lattice with unit cell dimensions; a= 10.84 Angstroem, b= 24.12 Angstroem, and c= 28.74 Angstroem.

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