625-61-6

Basic information

• Product Name: ethylsulfanylmethanethioamide
• Synonyms: ethylsulfanylmethanethioamide;Dithiocarbamic acid ethyl ester;Carbamodithioic acid,ethyl ester
• CAS NO: 625-61-6
• Molecular Formula: C₃H₇NS₂
• Molecular Weight: 121.22
• Mol File: 625-61-6.mol

Chemical Properties

• Boiling Point: 199.2 °C at 760 mmHg
• Flash Point: 74.3 °C
• Appearance: /
• Density: 1.203 g/cm³
• Vapor Pressure: 0.346mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: ethylsulfanylmethanethioamide(CAS DataBase Reference)
• NIST Chemistry Reference: ethylsulfanylmethanethioamide(625-61-6)
• EPA Substance Registry System: ethylsulfanylmethanethioamide(625-61-6)

Safety Data

• Hazardous Substances Data: 625-61-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Ethylsulfanylmethanethioamide is used as a building block in organic synthesis for its versatile chemical properties and reactivity, enabling the creation of a wide range of organic compounds.
Used in Chemical Research:
Ethylsulfanylmethanethioamide is used as a research compound to study its chemical properties and potential applications in various fields.
Used in Pharmaceutical Industry:
Ethylsulfanylmethanethioamide is used as a starting material for the development of new medicines and drugs, leveraging its potential biological activities and chemical versatility.
Used in Antibacterial Applications:
Ethylsulfanylmethanethioamide is used as an antibacterial agent due to its potential biological activities, helping to combat bacterial infections.
Used in Antifungal Applications:
Ethylsulfanylmethanethioamide is used as an antifungal agent, utilizing its potential biological activities to treat fungal infections.

InChI:InChI=1/C3H7NS2/c1-2-6-3(4)5/h2H2,1H3,(H2,4,5)

Upstream product

• 542-90-5 ethyl isothiocyanate 
• 7647-01-0 hydrogenchloride 
• 6322-61-8 N-acetyldithiocarbamic acid ethyl ester 
• 7783-06-4 hydrogen sulfide 
• 75-03-6 ethyl iodide 
• 513-74-6 ammonium dithiocarbamate 

Downstream Products

• 6322-61-8 N-acetyldithiocarbamic acid ethyl ester 
• 5316-74-5 2-ethylsulfanyl-4-phenyl-thiazole 
• 21076-24-4 2-Ethyl-1-phenyl-thiosemicarbazid 
• 21076-08-4 2-methyl-1-phenyl thiosemicarbazide 
• 75-15-0 carbon disulfide 
• 542-90-5 ethyl isothiocyanate 
• 7783-06-4 hydrogen sulfide 
• 75-08-1 ethanethiol 
• 1147550-11-5 ammonium thiocyanate 
• 953822-10-1 ethyl 3-phenyl-1-(p-toluenesulfonyl)propylcarbamodithioate 
• 28126-47-8 ethyl phenyl(p-toluenesulfonyl)methylcarbamodithioate 
• 1455272-68-0 4-(4-methoxyphenyl)-5-(4-chlorophenyl)-2-(ethylthio)-thiazole 
• 857419-85-3 1,5-di-pyrrol-2-yl-3-thia-pentane-1,5-dione 

Relevant articles and documents

Synthesis, cytotoxic evaluation, and molecular docking study of 4,5-diaryl-thiazole-2-thione analogs of combretastatin A-4 as microtubule-binding agents

A series of combretastatin A-4 analogs in which cis-olefinic bond replaced by thiazole ring were prepared by reaction of α-bromo-1,2-(p-substituted) diaryl-1-ethanones and dithiocarbamate derivatives. The cytotoxicity of these compounds was determined against three cancer cell lines (HT-29), (MCF-7), (AGS) as well as fibroblastic cell line (NIH-3T3) using MTT assay. Inhibition of tubulin polymerization for some potent compounds was evaluated. These biological studies proved that 6j and 6o were the most potent compounds in this series. Furthermore 2-(methylthio)-substituted compounds show moderate or no activity. Docking studies involving 6j and 6o demonstrated that this analogs could be successfully docked in the colchicine binding site of α,β-tubulin.