676148-40-6

Basic information

• Product Name: 3,8-Diazabicyclo[3.2.1]octane-2-carboxylicacid,4-oxo-,methylester,(1R,2R,5S)-(9CI)
• Synonyms: 3,8-Diazabicyclo[3.2.1]octane-2-carboxylicacid,4-oxo-,methylester,(1R,2R,5S)-(9CI);MMETHYL (2R)-4-OXO-3,8-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXYLATE
• CAS NO: 676148-40-6
• Molecular Formula: C8 H12 N2 O3
• Molecular Weight: 184.19
• Product Categories: PIPERIDINE
• Mol File: 676148-40-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,8-Diazabicyclo[3.2.1]octane-2-carboxylicacid,4-oxo-,methylester,(1R,2R,5S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3,8-Diazabicyclo[3.2.1]octane-2-carboxylicacid,4-oxo-,methylester,(1R,2R,5S)-(9CI)(676148-40-6)
• EPA Substance Registry System: 3,8-Diazabicyclo[3.2.1]octane-2-carboxylicacid,4-oxo-,methylester,(1R,2R,5S)-(9CI)(676148-40-6)

Safety Data

• Hazardous Substances Data: 676148-40-6(Hazardous Substances Data)

Upstream product

• 173142-47-7 methyl (2S)-5-methoxy-3,4-dihydro-2H-pyrrole-2-carboxylate 
• 4931-66-2 methyl (S)-pyroglutamate 
• 137131-35-2 5-methoxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid methyl ester 

Relevant articles and documents

Synthesis of orthogonally protected 3,8-diazabicyclo[3.2.1]octane-2- carboxylic acid - A versatile building block for the synthesis of cocaine analogues

An eight-step synthesis of an orthogonally protected 3,8-diazabicyclo[3.2. 1]octane from commercially available pyroglutamic acid was developed. The target compound can be used as a versatile building block for combinatorial synthesis of pharmacologically useful compounds and features a hidden α-, β-, δ- and ε-amino acid, which can also be seen as an example of a new class of cocaine analogues.

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