69098-08-4

Basic information

• Product Name: methyl 3-(4-methoxyphenyl)-3-methoxypropanoate
• Synonyms: methyl 3-(4-methoxyphenyl)-3-methoxypropanoate
• CAS NO: 69098-08-4
• Molecular Weight: 224.257
• Mol File: 69098-08-4.mol

Chemical Properties

• CAS DataBase Reference: methyl 3-(4-methoxyphenyl)-3-methoxypropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(4-methoxyphenyl)-3-methoxypropanoate(69098-08-4)
• EPA Substance Registry System: methyl 3-(4-methoxyphenyl)-3-methoxypropanoate(69098-08-4)

Safety Data

• Hazardous Substances Data: 69098-08-4(Hazardous Substances Data)

Upstream product

• 637-69-4 4-Methoxystyrene 
• 107-31-3 Methyl formate 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 463-51-4 Ketene 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 

Downstream Products

• 3901-07-3 3-(4-methoxy-phenyl)acrylic acid methyl ester 
• 5466-77-3 2-ethylhexyl methoxycinnamate 

Relevant articles and documents

Copper-Catalyzed 1,2-Methoxy Methoxycarbonylation of Alkenes with Methyl Formate

Reported here is a copper-catalyzed 1,2-methoxy methoxycarbonylation of alkenes by an unprecedented use of methyl formate as a source of both the methoxy and the methoxycarbonyl groups. This reaction transforms styrene and its derivatives into value-added β-methoxy alkanoates and cinnamates, as well as medicinally important five-membered heterocycles, such as functionalized tetrahydrofurans, γ-lactones, and pyrrolidines. A ternary β-diketiminato-CuI-styrene complex, fully characterized by NMR spectroscopy and X-ray crystallographic analysis, is capable of catalyzing the same transformation. These findings suggest that pre-coordination of electron-rich alkenes to copper might play an important role in accelerating the addition of nucleophilic radicals to electron-rich alkenes, and could have general implications in the design of novel radical-based transformations.

Palladium-catalyzed intermolecular Alkoxy-alkoxycarbonylation of Vinylphenols in the presence of copper salt: Unexpected cooperative effect of tin salt

Palladium-catalyzed intermolecular alkoxy-alkoxycarbonylation of vinylphenols under normal pressure of CO and O2 in alcohol was developed to afford the corresponding 3-alkoxy-3-arylpropanoates in good to high yields. Not only primary alcohols but also secondary alcohols were applicable to the present reaction. The presence of a tin salt was crucial to realize reproducibly high yields.

Stereoselektive Insertion von Ketenen in O,O-Acetale: Synthese von β-Alkoxyestern und 1,4-Dioxepan-5-onen

Keywords: Acetale; Aldoladditionen; Dioxepanone; Ketene

SYNTHESE, EIGENSCHAFTEN UND CARBONYL-INSERTIONS-REAKTIONEN VON TETRACARBONYLEISEN(0)-KOMPLEXEN para-SUBSTITUIERTER STYROLE

The Fe(CO)4 η2-complexes of para-substituted styrenes (substituent=H, CH3, OCH3, Cl, F) can be obtained in good yields.Complexation changes drastically the chemical shifts and coupling constants of the vinyl protons.Reaction of the complexes wi