760117-50-8Relevant articles and documents
The reduction of specific disulfides with titanium(III) chloride
Akers, Hugh A.,Vang, Meng C.,Updike, Tracie D.
, p. 1364 - 1366 (2007/10/02)
The reaction between titanium(III) chloride and disulfides was investigated.Aryl and alkyl disulfides did not react while heterocyclic aromatic disulfides with a nitrogen α to the sulfur were reduced to the corresponding thiols.Products were identified and characterized by nuclear magnetic resonance and inrared spectra; and melting point comparisons with authentic compounds.The reductions occurred only in the presence of citrate and were found to require 2 moles of titanium(III) per mole of disulfide.
Studies of thiaheterocyclic derivatives. I. Synthesis and pharmacological screening
Delarge,Thunus,Beckers,et al.
, p. 559 - 565 (2007/10/02)
The synthesis of several sulfured heterocyclic compounds has been carried out. They were examined for their antithyroid activity by preliminary screening in rats. The most interesting products are 1-methylimidazolylpyrimidylsulfides. They do not appear as 'pro drugs' of MMI.