842136-32-7

Basic information

• Product Name: Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester
• Synonyms: Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester;Methyl 5-broMo-2-(trifluoroMethyl)benzoate;Methyl 5-bromo-2-(trifluoromethyl)
• CAS NO: 842136-32-7
• Molecular Formula: C₉H₆BrF₃O₂
• Molecular Weight: 283.0419496
• Mol File: 842136-32-7.mol

Chemical Properties

• Boiling Point: 280.9±40.0 °C(Predicted)
• Appearance: /
• Density: 1.598±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester(842136-32-7)
• EPA Substance Registry System: Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester(842136-32-7)

Safety Data

• Hazardous Substances Data: 842136-32-7(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Benzoic acid, 5-bromo-2-(trifluoromethyl)-, methyl ester is used as a reagent in organic synthesis for its distinctive chemical characteristics, facilitating the creation of a range of organic compounds.
Used in Pharmaceutical Production:
Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester serves as a building block in the production of pharmaceuticals, contributing to the development of new medications due to its specific structural features.
Used in Agrochemicals:
Benzoic acid, 5-bromo-2-(trifluoromethyl)-, methyl ester is also utilized in the creation of agrochemicals, playing a role in the synthesis of substances that help protect and enhance crop yields.
Used as an Intermediate in Industrial Applications:
Furthermore, it is employed as an intermediate in the synthesis of various compounds for industrial applications, showcasing its broad utility across different sectors.

Upstream product

• 680-15-9 2,2-difluoro-2-(fluorosulfonyl)acetate 
• 181765-86-6 5-bromo-2-iodo-benzoic acid methyl ester 
• 1717-59-5 2,2-difluoro-2-(fluorosulfonyl)acetic acid 
• 21740-00-1 5-bromo-2-iodo-benzoic acid 

Downstream Products

• 654-97-7 5-bromo-2-(trifluoromethyl)benzoic acid 

Relevant articles and documents

ETHYNYL COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC USE FOR THE TREATMENT OF MALARIA

The present disclosure relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof wherein R1 means a fluorine atom or a perhalogeno linear alkyl radical containing 1, 2 or 3 carbon atoms; R2 means a chlorine atom, a linear alkyl radical containing 1, 2 or 3 carbon atoms or a perhalogeno linear alkyl radical containing 1, 2 or 3 carbon atoms, and R means a hydrogen atom or a radical of formula (la). The present disclosure also relates to processes for their preparation as well their therapeutic uses, in particular such as for use in the treatment of malaria.

COMPOUND HAVING ZNF143 INHIBITORY ACTIVITY AND USE THEREOF

PROBLEM TO BE SOLVED: To provide a compound having a ZNF143 inhibitory activity as well as to provide a ZNF143 inhibitory agent and pharmaceutical composition containing the same. SOLUTION: Provided is a compound represented by formula (I) or a salt thereof as well as a ZNF143 inhibitory agent containing the same and a pharmaceutical composition having the same as an active ingredient. A-B-C-D (I)[A is H, a methyl group, a naphthyl group, a phenyl group or a nitrogen-containing heterocyclic ring; B is as shown below, and C is an amide bond or a heteroaromatic ring containing N and O; D is a substituted/unsubstituted phenyl group or a monocyclic heteroaromatic ring containing N or S; and C and D are both fused heterocyclic ring or the like optionally having a substituent group.]. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2016,JPOandINPIT

PYRAZOLE PYRAZINE AMINE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS THEREOF AND METHODS OF TREATMENT THEREWITH

Provided herein are Pyrazole Pyrazine Amine Compounds having the following structure:Formula (I). Wherein Q and R1-R3 are as defined herein, compositions comprising an effective amount of a Pyrazole Pyrazine Amine Compound and methods for treating or preventing inflammatory conditions, immunological conditions, cancer, neurodegenerative diseases, age-related diseases, cardiovascular diseases and metabolic conditions, or conditions treatable or preventable by inhibition of an IKK, or an IKK pathway, comprising administering an effective amount of a Pyrazole Pyrazine Amine Compound to a patient in need thereof.