845644-47-5Relevant articles and documents
INDOLE ACETIC ACIDS EXHIBITING CRTH2 RECEPTOR ANTAGONISM AND USES THEREOF
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Page/Page column 64-65, (2008/06/13)
The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metab
Synthesis of fused sulfonamide (1,1-dioxoisothiazole)substituted 1,5-diarylpyrazoles as cyclooxygenase inhibitors
Pal, Manojit,Veeramaneni, Venugopal Rao,Kumar, Sanjeev,Lohray, Vidya B.,Yeleswarapu, Koteswar Rao
, p. 1095 - 1101 (2007/10/03)
First synthesis of novel 1,1-dioxo-2,3-dihydrobenzo[d] isothiazolyl substituted 1,5-diarylpyrazoles has been accomplished via oxidative cyclization of 4-fluoro-2-methyl benzenesulfonamide followed by the treatment with hydrazine and then with 1,3-dicarbon