869109-31-9

Usage

Uses

Used in Pharmaceutical Industry:
Diisopropyl 3-hydroxycyclobutane-1,1-dicarboxylate is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, Diisopropyl 3-hydroxycyclobutane-1,1-dicarboxylate serves as an essential intermediate in the production of agrochemicals. Its properties allow for the creation of compounds that can be used in pest control and crop protection, enhancing agricultural productivity.
Used in Chemical Manufacturing:
Diisopropyl 3-hydroxycyclobutane-1,1-dicarboxylate is utilized in the chemical manufacturing industry as a versatile building block for the synthesis of a wide range of organic compounds. Its presence in various chemical processes highlights its importance in the development of new materials and products.
It is crucial to handle Diisopropyl 3-hydroxycyclobutane-1,1-dicarboxylate with care and adhere to proper safety protocols when working with it in laboratory or industrial settings to ensure the safety of personnel and the environment.

Upstream product

• 893724-10-2 dipropan-2-yl 3-oxocyclobutane-1,1-dicarboxylate 
• 869109-30-8 dipropan-2-yl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate 

Downstream Products

• 1403767-29-2 diisopropyl 3-fluorocyclobutane-1,1-dicarboxylate 
• 893724-10-2 dipropan-2-yl 3-oxocyclobutane-1,1-dicarboxylate 

Relevant academic research and scientific papers

Fluorine-Labelled Spiro[3.3]heptane-Derived Building Blocks: Is Single Fluorine the Best?

A reliable methodology for constructing 6-fluoro-spiro[3.3]heptane scaffold is developed. A vast library of 2-mono- and 2,2-difunctionalized 6-fluoro-spiro[3.3]heptane-derived building blocks were obtained in a multigram scale (up to 302 g) though the convergent synthetic strategy. This class of compounds was designed for medicinal chemistry as fluorine-labelled conformationally restricted isosteres of cyclohexane framework. The structure was confirmed by X-ray diffraction study, and the physico-chemical properties (acidity, lipophilicity and water solubility) were characterized. Finally, the generation of virtual compound libraries using the LLAMA software showed that the monofluorinated spiro[3.3]heptane-derived building blocks demonstrated the highest propensity to populate the lead-like chemical space as compared to non- and difluorinated counterparts, as well as cyclohexane derivatives, while retaining similar three-dimensionality features.

NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION

The invention provides novel compounds having the general formula:(I) wherein R1, R2, R3, R4, W and X are as described herein, compositions including the compounds and methods of using the compounds.

IMIDAZOPYRIDINE COMPOUND

The present invention provides an imidazopyridine compound represented by formula (I), wherein R1 and R2 each independently represent a C1-6 alkyl group et al; R3 and R4 each independently represent a hydrogen atom, a methyl et al; Ar1 is a divalent substituent representing a monocyclic or bicyclic, 3- to 8-membered aromatic or aliphatic heterocyclic group et al; Ar2 represents an aromatic carbocyclic group, or an aromatic heterocyclic group; W represents -(CH2)m et al, and m indicates an integer of from 0 to 10. This compound acts as a melanin concentrating hormone receptor antagonist, and is useful as treating agents for obesity.