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1H-Pyrrole-2-acetic acid, 3-(methoxycarbonyl)-1-methyl-, methyl ester is a chemical compound characterized by the molecular formula C11H13NO3. It is a methyl ester derivative of 1H-pyrrole-2-acetic acid, a pyrrole derivative that serves as a significant building block in medicinal chemistry. The presence of the methoxycarbonyl group, a common protective group in organic synthesis, endows 1H-Pyrrole-2-acetic acid, 3-(methoxycarbonyl)-1-methyl-, methyl ester with unique structural features and reactivity. Due to its potential applications in pharmaceuticals and organic synthesis, it is essential to handle this chemical with care and adhere to all safety protocols in the laboratory.

871819-39-5

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871819-39-5 Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrrole-2-acetic acid, 3-(methoxycarbonyl)-1-methyl-, methyl ester is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structural features and reactivity make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 1H-Pyrrole-2-acetic acid, 3-(methoxycarbonyl)-1-methyl-, methyl ester is utilized as a versatile reagent for the preparation of a wide range of organic compounds. The methoxycarbonyl group serves as a protective group, allowing for selective reactions and facilitating the synthesis of complex organic molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 871819-39-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,8,1 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 871819-39:
(8*8)+(7*7)+(6*1)+(5*8)+(4*1)+(3*9)+(2*3)+(1*9)=205
205 % 10 = 5
So 871819-39-5 is a valid CAS Registry Number.

871819-39-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-(2-methoxy-2-oxoethyl)-1-methylpyrrole-3-carboxylate

1.2 Other means of identification

Product number -
Other names 2-methoxycarbonylmethyl-1-rnethyl-1H-pyrrole-3-carboxylic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:871819-39-5 SDS

871819-39-5Downstream Products

871819-39-5Relevant articles and documents

Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin- 7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain

Giblin, Gerard M. P.,Billinton, Andrew,Briggs, Michael,Brown, Andrew J.,Chessell, Iain P.,Clayton, Nick M.,Eatherton, Andrew J.,Goldsmith, Paul,Haslam, Carl,Johnson, Matthew R.,Mitchell, William L.,Naylor, Alan,Perboni, Alcide,Slingsby, Brian P.,Wilson, Alex W.

supporting information; experimental part, p. 5785 - 5788 (2010/02/28)

We report the synthesis and SAR of a series of novel azaindole CB 2 agonists. 6-Azaindole 18 showed activity in an acute pain model but was inactive in a chronic model. 18 is a Pgp substrate with low brain penetration. The template was redesign

COMBINATION OF CB2 LIGAND AND PARACETAMOL

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Page/Page column 135, (2008/12/04)

Combination of one or more CB2 modulators and paracetamol are useful of treating conditions which are mediated by the activity of CB2 receptors such as an immune disorder, an inflammatory disorder, pain, rheumatoid arthritis, multiple sclerosis, osteoarthritis, and osteoporosis.

PYRROLOPYRIDINE DERIVATIVES

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, (2008/06/13)

The present invention relates to novel pyrrolopyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.

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