87240-06-0

Basic information

• Product Name: 7-BROMO-5-NITROINDOLINE
• Synonyms: 7-Bromo-5-nitro-2,3-dihydro-1H-indole;7-BROMO-5-NITROINDOLINE ;7-Bromo-5-nitro-1H-indoline;NSC 283852
• CAS NO: 87240-06-0
• Molecular Formula: C₈H₇BrN₂O₂
• Molecular Weight: 243.05738
• Mol File: 87240-06-0.mol

Chemical Properties

• Melting Point: 149-151℃
• Boiling Point: 356°C at 760 mmHg
• Flash Point: 169.1°C
• Appearance: /
• Density: 1.704g/cm³
• Vapor Pressure: 3.01E-05mmHg at 25°C
• Refractive Index: 1.64
• Storage Temp.: 2-8°C(protect from light)
• PKA: -1.03±0.20(Predicted)
• CAS DataBase Reference: 7-BROMO-5-NITROINDOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BROMO-5-NITROINDOLINE(87240-06-0)
• EPA Substance Registry System: 7-BROMO-5-NITROINDOLINE(87240-06-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 87240-06-0(Hazardous Substances Data)

Usage

Uses

Used in Scientific Research Applications:
7-BROMO-5-NITROINDOLINE is used as a research chemical for its unique combination of bromine and nitrogen properties, which can contribute to specific potential reactivity and utilization in scientific studies and experiments.
Used in Chemical Synthesis:
7-BROMO-5-NITROINDOLINE is used as a chemical intermediate in the synthesis of various organic compounds, taking advantage of its reactive bromine and nitrogen groups for the formation of new chemical bonds and structures.
Used in Material Science:
7-BROMO-5-NITROINDOLINE is used as a component in the development of new materials with specific properties, such as flame retardants or polymers, due to its organobromine nature and reactivity.

InChI:InChI=1/C8H7BrN2O2/c9-7-4-6(11(12)13)3-5-1-2-10-8(5)7/h3-4,10H,1-2H2

Upstream product

• 32692-19-6 5-nitro-2,3-dihydro-1H-indole 
• 33632-27-8 1-(5-nitro-2,3-dihydroindol-1-yl)ethanone 
• 16078-30-1 1-Acetyl-2,3-dihydro-1H-indole 

Downstream Products

• 10553-08-9 7-methyl-5-nitro-1H-indole 
• 1610800-25-3 4-amino-6-(7-cyclopropyl-1-propyl-1H-indol-5-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 120-72-9 indole 
• 114144-24-0 1-acetyl-2,3-dihydro-7-bromoindole 
• 132905-12-5 2-Benzyloxy-4,5-dihydro-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-7-one 
• 132905-13-6 2-Benzyloxy-4,5-dihydro-7H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine 
• 97438-92-1 ungeremine 
• 40360-71-2 anhydrolycorine-7-one 
• 52886-06-3 hippadine 
• 5318-11-6 5-Amino-indol-3-essigsaeure 
• 5192-03-0 5-amino-1H-indole 
• 87240-07-1 7-bromo-5-nitro-1H-indole 
• 220442-80-8 1-acetyl-7-bromo-5-nitro-indoline 

Relevant articles and documents

NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS

This invention relates to novel compounds which are inhibitors of acyl coenzyme A: diacylglycerol acyltransferase 1 (DGAT-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in comb

NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS

This invention relates to novel compounds which are inhibitors of acyl coenzyme A: diacylglycerol acyltransferase 1 (DGAT-1 ), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination with weight management therapies or other triglyceride lowering therapy for the prevention or treatment of diseases related to DGAT-1 dysfunction or where modulation of DGAT-1 activity may have therapeutic benefit.

NOVEL 6-5 BICYCIC HETEROCYCLIC DERIVATIVE AND MEDICAL USE THEREOF

An object of the present invention is to provide a medicament as a thyroid hormone receptor ligand which is sufficient in drug efficacy and safety, and has the excellent action as a drug. The present invention provides a compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof: [wherein [Chemical Formula 2] is a single bond or a double bond; A is -CH2- or -CO-; X, Y, and Z are each independently a nitrogen atom or a carbon atom; R1 is a hydrogen atom or an aralkyl group; R2 is an alkyl group or an aralkyl group, etc.; R3 is a hydrogen atom or an alkyl group, etc.; R4 is a hydrogen atom or an alkyl group; R5 is a hydrogen atom, an alkyl group or a halo lower alkyl group, etc.; R6 is a hydrogen atom or an alkyl group; R7 is a hydrogen atom, etc.; R8 is a hydrogen atom, or an alkyl group, etc.; and E is -NHCO-G-COR12, etc. (wherein G is a single bond or an alkylene group, and R12 is a hydroxy group or an alkoxy group)].

5- AND 6-(2-IMIDAZOLIN-2-YLAMINO) AND -(2-THIAZOLIN-2-YLAMINO)-BENZOTHIAZOLES AS ALPHA-2 ADRENERGIC LIGANDS

This invention is directed to indole and benzothiazole compounds which are selective for cloned human alpha 2 receptors. This invention is also related to uses of these compounds for any indication where use of an alpha 2 agonist may be appropriate. Specifically, this includes use as analgesic, sedative and anaesthetic agents. In addition, this invention includes using such compounds for lowering intraocular pressure, presbyopia, treating migraine, hypertension, alcohol withdrawal, drug addiction, rheumatoid arthritis, ischemic pain, spasticity, diarrhea, nasal decongestion, urinary incontinence as well as for use as cognition enhancers and ocular vasoconstriction agents. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.

SPECIFICALLY DEUTERATED AND TRITIATED AUXINS

Regiospecific synthesis of monodeuterated and monotritiated natural auxin (indole-3-acetic acid), a synthetic auxin (naphthalene-1-acetic acid) and a photoaffinity labeling auxin (5-azidoindole-3-acetic acid) are described.These synthesis provide benzene-ring tritiated auxins for use in reversible and covalent binding studies. - Key Word Index: Auxin; azido auxin; indole-3-acetic acid; 5-azidoindole-3-acetic acid; napthalene-1-acetic acid; radiolabeling; photoaffinity labeling; synthesis.