881844-11-7

Basic information

• Product Name: 4-chloro-1-(4-Methoxybenzyl)-1H-iMidazo[4,5-c]pyridine
• Synonyms: 4-chloro-1-(4-Methoxybenzyl)-1H-iMidazo[4,5-c]pyridine;4-chloro-1-(4-Methoxybenzyl)-1H-iMidazo[4,5-c]pyridine-5
• CAS NO: 881844-11-7
• Molecular Formula: C₁₄H₁₂ClN₃O
• Molecular Weight: 273.71758
• Mol File: 881844-11-7.mol

Chemical Properties

• Boiling Point: 483.0±55.0 °C(Predicted)
• Appearance: /
• Density: 1.31±0.1 g/cm3(Predicted)
• PKA: 3.11±0.30(Predicted)
• CAS DataBase Reference: 4-chloro-1-(4-Methoxybenzyl)-1H-iMidazo[4,5-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-1-(4-Methoxybenzyl)-1H-iMidazo[4,5-c]pyridine(881844-11-7)
• EPA Substance Registry System: 4-chloro-1-(4-Methoxybenzyl)-1H-iMidazo[4,5-c]pyridine(881844-11-7)

Safety Data

• Hazardous Substances Data: 881844-11-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine is used as a potential candidate for the development of new drugs due to its unique chemical structure and possible therapeutic effects.
Used in Research and Development:
In the fields of medicine and biochemistry, 4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine serves as a valuable compound for research and development, aiding in the discovery and understanding of new pharmaceutical agents and their mechanisms of action.
Safety Precautions:
It is crucial to handle 4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine with care and adhere to proper safety measures to mitigate any potential hazards associated with its use.

Upstream product

• 2770-01-6 4-chloro-1H-imidazo[4,5-c]pyridine 
• 824-94-2 p-methoxybenzyl chloride 
• 39217-08-8 2-chloropyridine-3,4-diamine 
• 2789-25-5 2-chloro-3-nitropyridin-4-amine 
• 14432-12-3 4-Amino-2-chloropyridine 
• 14432-16-7 2-chloro-4-nitropyridine-N-oxide 
• 2402-95-1 2-chloropyridine-N-oxide 
• 109-09-1 2-chloropyridine 
• 5975-12-2 2,4-dichloro-3-nitro-pyridine 
• 89282-12-2 2,4-dihydroxy-3-nitropyridine 
• 881844-09-3 2-chloro-N-(4-methoxybenzyl)-3-nitropyridin-4-amine 
• 881844-10-6 2-chloro-N⁴-(4-methoxybenzyl)pyridine-3,4-diamine 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 1313714-36-1 4-(furan-2-yl)-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine 
• 6811-77-4 3-deazaadenine 
• 881844-18-4 4-amino-3-[2'-deoxy-3',5'-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl]-7-nitro-3H-imidazo[4,5-c]pyridine 
• 881844-13-9 4-amino-1-[2'-deoxy-3',5'-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl]-7-nitro-1H-imidazo[4,5-c]pyridine 
• 881844-12-8 4-(isobutyrylamino)-1H-imidazo[4,5-c]pyridine 
• 3243-26-3 4-hydrazino-1H-imidazo[4,5-c]pyridine 

Relevant articles and documents

Design and synthesis of purine analogues as highly specific ligands for FcyB, a ubiquitous fungal nucleobase transporter

In the course of our study on fungal purine transporters, a number of new 3-deazapurine analogues have been rationally designed, based on the interaction of purine substrates with the Aspergillus nidulans FcyB carrier, and synthesized following an effective synthetic procedure. Certain derivatives have been found to specifically inhibit FcyB-mediated [3H]-adenine uptake. Molecular simulations have been performed, suggesting that all active compounds interact with FcyB through the formation of hydrogen bonds with Asn163, while the insertion of hydrophobic fragments at position 9 and N6 of 3-deazaadenine enhanced the inhibition.

Synthesis of 3-deaza-3-nitro-2′-deoxyadenosine

Photoactivable deoxyadenosine mimic, 3-deaza-3-nitro-2′- deoxyadenosine (2), was prepared using two different synthetic routes. The first route involved base catalyzed glycosylation of 3-deaza-3-nitroadenine, which was prepared by regioselective nitration