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1-(2-chlorothiazol-5-yl)ethanone, also known as 1-(2-chloro-1,3-thiazol-5-yl)ethan-1-one, is a chemical compound with the molecular formula C6H5ClN0S. It is a ketone derivative featuring a thiazole ring and a chlorine atom attached to it, known for its versatile reactivity and potential in the synthesis of pharmaceuticals and agrochemicals.

885229-41-4

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885229-41-4 Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2-chlorothiazol-5-yl)ethanone is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique structure and reactivity allow it to participate in a wide range of chemical reactions, making it a valuable component in the development of new medications with diverse therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 1-(2-chlorothiazol-5-yl)ethanone serves as an intermediate for the production of various agrochemicals. Its potential as a building block in the development of new compounds with biological activity and medicinal properties makes it a promising candidate for creating innovative solutions in agriculture.
Used in Organic Chemistry Research:
1-(2-chlorothiazol-5-yl)ethanone is also of interest in the field of organic chemistry research. Its reactivity and potential applications in the development of new synthetic methods and strategies contribute to the advancement of chemical science and the creation of novel compounds with potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 885229-41-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,2 and 9 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 885229-41:
(8*8)+(7*8)+(6*5)+(5*2)+(4*2)+(3*9)+(2*4)+(1*1)=204
204 % 10 = 4
So 885229-41-4 is a valid CAS Registry Number.

885229-41-4Relevant articles and documents

PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE

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, (2021/04/10)

The present invention relates to a process for the preparation 2-chloro-1-(2-chlorothiazol-5-yl)ethanone.

Second generation of thiazolylmannosides, FimH antagonists for E. coli-induced Crohn's disease

Chalopin,Alvarez Dorta,Sivignon,Caudan,Dumych,Bilyy,Deniaud,Barnich,Bouckaert,Gouin

, p. 3913 - 3925 (2016/05/19)

The anti-adhesive strategy, consisting of disrupting bacterial attachment to the host cells, is widely explored as an alternative to antibiotic therapies. Recently, thiazolylmannosides (TazMans) have been identified as strong anti-adhesives of E. coli strains implied in the gut inflammation of patients with Crohn's disease. In this work, we developed a second generation of TazMans with improved chemical stability. The anomeric nitrogen was substituted by short linkers and the compounds were assessed against the bacterial adhesin FimH and the clinically isolated LF82 E. coli strain in four in vitro assays. The results obtained on the FimH adhesin alone and the whole bacteria enabled the identification of a candidate for further in vivo evaluations.

MULTIMERIC MANNOSIDES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG

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Page/Page column 133; 134, (2014/02/16)

The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia Coli infections. Exemplary compounds are:

HETEROARYL COMPOUNDS USEFUL AS RAF KINASE INHIBITORS

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Page/Page column 74; 75, (2010/08/04)

The present invention provides compounds of formula (I) useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf -mediated diseases.

Thieno-pyrimidine compounds having fungicidal activity

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Page/Page column 10, (2008/06/13)

The present invention relates to thieno[2,3-d]-pyrimidine compounds having fungicidal activity.

THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY

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Page/Page column 33, (2008/06/13)

The present invention relates to thieno[2,3-d]-pyrimidine compounds of Formula (I) having fungicidal activity.

Thieno-pyrimidine compounds having fungicidal activity

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Page/Page column 35, (2010/11/08)

The present invention relates to thieno[2,3-d]-pyrimidine compounds having fungicidal activity.

AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE

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Page/Page column 33, (2010/11/08)

The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.

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