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2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE is a heterocyclic chemical compound belonging to the benzooxazole class. It features a benzene ring fused to an oxazole ring, with a pharmacologically significant piperazine group attached to the benzene ring. 2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE is recognized for its potential biological activity and is extensively utilized in medicinal chemistry research and drug development due to the diverse therapeutic properties of its constituent groups.

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  • 885275-02-5 Structure
  • Basic information

    1. Product Name: 2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE
    2. Synonyms: 2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE;2-(4-(piperazin-1-yl)phenyl)benzo[d]oxazole
    3. CAS NO:885275-02-5
    4. Molecular Formula: C17H17N3O
    5. Molecular Weight: 279.34
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 885275-02-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE(885275-02-5)
    11. EPA Substance Registry System: 2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE(885275-02-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 885275-02-5(Hazardous Substances Data)

885275-02-5 Usage

Uses

Used in Pharmaceutical Research and Development:
2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE is used as a key compound in pharmaceutical research and development for its potential applications in various therapeutic areas. The piperazine group, known for its broad range of pharmacological effects, and the benzooxazole ring, which has been studied for anticancer, antimicrobial, and antiviral properties, contribute to the compound's multifaceted utility in creating new drugs.
Used in Anticancer Agents Development:
In the field of oncology, 2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE is used as a precursor or building block in the development of anticancer agents. Its structure allows for the design of molecules that can target specific cancer-related pathways or interact with cellular components to inhibit tumor growth and proliferation.
Used in Antimicrobial Agents Development:
2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE is also utilized in the development of antimicrobial agents, given the antimicrobial potential of benzooxazoles. This makes it a candidate for creating new antibiotics or antifungal compounds to combat drug-resistant infections.
Used in Antiviral Agents Development:
In antiviral research, 2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOXAZOLE is used as a component in the design of antiviral drugs. Its unique structure may facilitate the development of compounds that can inhibit viral replication or disrupt viral life cycles, offering new treatment options for viral diseases.
Used in Medicinal Chemistry:
2-(4-PIPERAZIN-1-YL-PHENYL)-BENZOOXAZOLE is used as a versatile building block in medicinal chemistry for the synthesis of various bioactive molecules. Its ability to be modified and combined with other chemical groups makes it a valuable component in the creation of compounds with specific therapeutic targets and improved pharmacokinetic properties.

Check Digit Verification of cas no

The CAS Registry Mumber 885275-02-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 885275-02:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*5)+(2*0)+(1*2)=205
205 % 10 = 5
So 885275-02-5 is a valid CAS Registry Number.

885275-02-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-piperazin-1-ylphenyl)-1,3-benzoxazole

1.2 Other means of identification

Product number -
Other names Benzoxazole,2-[4-(1-piperazinyl)phenyl]

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:885275-02-5 SDS

885275-02-5Relevant articles and documents

Discovery and preliminary structure-activity relationship of arylpiperazines as novel, brain-penetrant antiprion compounds

Li, Zhe,Gever, Joel R.,Rao, Satish,Widjaja, Kartika,Prusiner, Stanley B.,Silber, B. Michael

supporting information, p. 397 - 401 (2013/06/27)

Creutzfeldt-Jakob disease and kuru in humans, BSE in cattle, and scrapie in sheep are fatal neurodegenerative disorders. Such illnesses are caused by the conversion and accumulation of a misfolded pathogenic isoform (termed PrP Sc) of a normall

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