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METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE, with the molecular formula C11H11NO3, is a chemical compound derived from indazole, a bicyclic aromatic heterocycle. It features a carboxylate ester functional group and is recognized for its diverse chemical and biological properties. METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE is a significant target for research and development in drug discovery, with potential applications in various fields.

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  • 885278-53-5 Structure
  • Basic information

    1. Product Name: METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
    2. Synonyms: METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE;1H-Indazole-3-carboxylic acid, 6-Methoxy-, Methyl ester;6-Methoxy-3-1H-indazole-carboxylic acid Methyl ester;6-Methoxy-1H-indazole-3-carboxylic acid methyl ester
    3. CAS NO:885278-53-5
    4. Molecular Formula: C10H10N2O3
    5. Molecular Weight: 206.2
    6. EINECS: 200-258-5
    7. Product Categories: N/A
    8. Mol File: 885278-53-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 382.235°C at 760 mmHg
    3. Flash Point: 184.969°C
    4. Appearance: /
    5. Density: 1.313g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.619
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. PKA: 12.22±0.40(Predicted)
    11. CAS DataBase Reference: METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE(CAS DataBase Reference)
    12. NIST Chemistry Reference: METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE(885278-53-5)
    13. EPA Substance Registry System: METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE(885278-53-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 885278-53-5(Hazardous Substances Data)

885278-53-5 Usage

Uses

Used in Pharmaceutical Industry:
METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE is used as a chemical intermediate for the synthesis of pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE is also used as an intermediate in the production of agrochemicals, contributing to the development of effective and innovative products for agricultural applications.
Used in Biological Research:
METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE is used as a subject of study for its potential biological activities, such as anti-inflammatory and analgesic properties. This research could lead to the discovery of new therapeutic agents and treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 885278-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 885278-53:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*8)+(2*5)+(1*3)=225
225 % 10 = 5
So 885278-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2O3/c1-14-6-3-4-7-8(5-6)11-12-9(7)10(13)15-2/h3-5H,1-2H3,(H,11,12)

885278-53-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name METHYL 6-METHOXY-1H-INDAZOLE-3-CARBOXYLATE

1.2 Other means of identification

Product number -
Other names 1H-Indazole-3-carboxylicacid,6-methoxy-,methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:885278-53-5 SDS

885278-53-5Downstream Products

885278-53-5Relevant articles and documents

ALKYNYL ALCOHOLS AND METHODS OF USE

-

Page/Page column 107; 168, (2015/03/13)

The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over- activation of NF-kB signaling is observed.

Synthesis of 3-indazolecarboxylic esters and amides via Pd-catalyzed carbonylation of 3-iodoindazoles

Buchstaller, Hans-Peter,Wilkinson, Kai,Burek, Kasimir,Nisar, Yasmin

, p. 3089 - 3098 (2011/10/13)

A straightforward and effective procedure for the preparation of 1H-indazole-3-carboxylic acid esters and amides was developed. A series of functionalized 3-iodoindazoles were subjected to Pd-catalyzed carbonylations in the presence of methanol or amines,

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