914636-97-8

Basic information

• Product Name: 3-METHOXY-4-NITROBENZOTRIFLUORIDE
• Synonyms: 3-METHOXY-4-NITROBENZOTRIFLUORIDE;2-Methoxy-1-nitro-4-(trifluoroMethyl)benzene;2-nitro-5-(trifluoromethyl)anisole
• CAS NO: 914636-97-8
• Molecular Formula: C8H6F3NO3
• Molecular Weight: 221.1333496
• Mol File: 914636-97-8.mol

Chemical Properties

• Boiling Point: 269.4±40.0 °C(Predicted)
• Appearance: /
• Density: 1.392±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-METHOXY-4-NITROBENZOTRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-4-NITROBENZOTRIFLUORIDE(914636-97-8)
• EPA Substance Registry System: 3-METHOXY-4-NITROBENZOTRIFLUORIDE(914636-97-8)

Safety Data

• Hazardous Substances Data: 914636-97-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
3-METHOXY-4-NITROBENZOTRIFLUORIDE is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new and effective products in these fields.
Used in Dye Production:
3-METHOXY-4-NITROBENZOTRIFLUORIDE is utilized as an intermediate in the production of dyes, playing a significant role in the creation of colorants for various applications.
Used in Organic Synthesis as a Reagent:
In the realm of organic synthesis, 3-METHOXY-4-NITROBENZOTRIFLUORIDE is employed as a reagent, facilitating various chemical reactions and contributing to the synthesis of complex organic compounds.

Upstream product

• 67-56-1 methanol 
• 402-12-0 2-fluoro-1-nitro-4-(trifluoromethyl)benzene 
• 402-17-5 2-nitro-5-trifluoromethylphenol 
• 77-78-1 dimethyl sulfate 
• 98-17-9 3-Trifluoromethylphenol 

Relevant articles and documents

QUINOLINONE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS

Disclosed herein are certain quinolinone derivatives of Formula (A) that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.

METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION

Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer. The present disclosure describes compounds and methods to recover wild-type function to p53 mutants. The compounds of the present invention can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA and activate downstream effectors involved in tumor suppression. The disclosed compounds can be used to reduce the progression of cancers that contain a p53 mutation.

Vapochromic Luminescent π-Conjugated Systems with Reversible Coordination-Number Control of Hypervalent Tin(IV)-Fused Azobenzene Complexes

The dynamic and reversible changes of coordination numbers between five and six in solution and solid states, based on hypervalent tin(IV)-fused azobenzene (TAz) complexes, are reported. It was found that the TAz complexes showed deep-red emission owing t