924868-81-5

Basic information

• Product Name: Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester
• Synonyms: Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester;2,5-Difluoro-4-nitrobenzoic acid methyl ester
• CAS NO: 924868-81-5
• Molecular Formula: C₈H₅F₂NO₄
• Molecular Weight: 217.1264064
• Mol File: 924868-81-5.mol

Chemical Properties

• Boiling Point: 318.3±42.0 °C(Predicted)
• Appearance: /Solid
• Density: 1.471±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester(924868-81-5)
• EPA Substance Registry System: Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester(924868-81-5)

Safety Data

• Hazardous Substances Data: 924868-81-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester is used as a building block for the synthesis of various pharmaceutical drugs. Its unique chemical structure allows for the development of new and effective medications, contributing to advancements in healthcare.
Used in Agricultural Industry:
In the agricultural sector, Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester serves as a key component in the production of agrochemicals. Its incorporation into these compounds aids in the development of more effective and targeted crop protection solutions.
Used in Fragrance and Flavor Industry:
Due to its aromatic properties, Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester is utilized in the creation of fragrances and flavors. It adds unique scents and tastes to various products, enhancing consumer experiences in the fragrance and flavor markets.
It is crucial to handle and store Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester with care, as it may pose health and environmental hazards if not properly managed. Proper handling protocols and storage conditions are essential to ensure the safety of individuals and the environment.

Upstream product

• 67-56-1 methanol 
• 116465-48-6 2,5‐difluoro‐4‐nitrobenzoic acid 

Downstream Products

• 1037834-49-3 di-tert-butyl [4-fluoro-5-(methoxycarbonyl)-2-nitrophenyl]malonate 
• 1001345-80-7 2‐fluoro‐5‐methoxy‐4‐nitrobenzoic acid 
• 1022947-91-6 methyl 2-fluoro-5-methoxy-4-nitrobenzoate 
• 1001346-91-3 4-amino-2-fluoro-5-methoxy-benzoic acid 
• 1137867-66-3 4-(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-2-fluoro-5-methoxy-benzoic acid 
• 1137868-52-0 TAK-960 
• 1160474-68-9 (2,5-difluoro-4-nitrophenyl)methanol 
• 1037834-51-7 di-tert-butyl [2-amino-4-fluoro-5-(methoxycarbonyl)phenyl]malonate 
• 1037834-54-0 1-{1-[(benzyloxy)carbonyl]piperidin-4-yl}-6-fluoro-2-oxoindoline-5-carboxylic acid 
• 1037834-53-9 methyl 1-{1-[(benzyloxy)carbonyl]piperidin-4-yl}-6-fluoro-2-oxoindoline-5-carboxylate 
• 1037834-55-1 benzyl 4-{6-fluoro-5-[(methylamino)carbonyl]-2-oxo-2,3-dihydro-1H-indol-1-yl}piperidine-1-carboxylate 
• 1037834-52-8 di-tert-butyl [2-({1-[(benzyloxy)carbonyl]piperidin-4-yl}amino)-4-fluoro-5-(methoxycarbonyl)phenyl]malonate 

Relevant articles and documents

INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS

The invention relates to indole carboxamide derivatives of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n are as defined in the description, their preparation and their use as pharmaceutically active compounds.

INHIBITORS OF SERINE PALMITOYLTRANSFERASE

This invention provides compounds of the formula (I) useful in the inhibition or modulation of serine palmitoyl transferase and their use in methods of treatment or amelioration of type 2 diabetes, type 1 diabetes, insulin resistance, the effects of obesity, metabolic syndrome (sometimes referred to as Syndrome X), impaired glucose tolerance, Cushing's disease, cardiovascular disease, prothrombotic conditions, myocardial infarction, hypertension, congestive heart failure, cardiomyopathy, atherosclerosis, dyslipidemia, sepsis, liver damage, retinal degenerative disorders, cachexia, emphysema, hepatitis C infections, HIV infections and inflammatory disorders and useful in methods for raising HDL plasma levels in a mammal. The compounds of this invention can also be used to prevent damage or loss of pancreatic islet beta cells (such as in the case of pancreatic beta cell apoptosis, including those related to insulin-dependent diabetes mellitus).