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2-Bromo-6-chlorobenzoic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 93224-85-2 Structure
  • Basic information

    1. Product Name: 2-Bromo-6-chlorobenzoic acid
    2. Synonyms: BUTTPARK 51\01-28;2-BROMO-6-CHLOROBENZOIC ACID;AKOS MSC-0781;3-bromo-2-chloro-benzoic acid;6-bromo-2-chloroBenzoic acid;Benzoic acid, 2-broMo-6-chloro-
    3. CAS NO:93224-85-2
    4. Molecular Formula: C7H4BrClO2
    5. Molecular Weight: 235.46
    6. EINECS: N/A
    7. Product Categories: blocks;Bromides;Carboxes;Benzoic acid;API intermediates;Acids & Esters;Bromine Compounds;Chlorine Compounds;Acids and Esters
    8. Mol File: 93224-85-2.mol
  • Chemical Properties

    1. Melting Point: 148-150°C
    2. Boiling Point: 315.883 °C at 760 mmHg
    3. Flash Point: 144.841 °C
    4. Appearance: /
    5. Density: 1.81 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.621
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. PKA: 1.62±0.10(Predicted)
    11. CAS DataBase Reference: 2-Bromo-6-chlorobenzoic acid(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-Bromo-6-chlorobenzoic acid(93224-85-2)
    13. EPA Substance Registry System: 2-Bromo-6-chlorobenzoic acid(93224-85-2)
  • Safety Data

    1. Hazard Codes: Xi,T
    2. Statements: 25-36/37/38
    3. Safety Statements: 26-45
    4. RIDADR: 2811
    5. WGK Germany: 2
    6. RTECS:
    7. HazardClass: IRRITANT
    8. PackingGroup:
    9. Hazardous Substances Data: 93224-85-2(Hazardous Substances Data)

93224-85-2 Usage

Chemical Properties

off-white powder

Check Digit Verification of cas no

The CAS Registry Mumber 93224-85-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,2,2 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 93224-85:
(7*9)+(6*3)+(5*2)+(4*2)+(3*4)+(2*8)+(1*5)=132
132 % 10 = 2
So 93224-85-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H4BrClO2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H,10,11)

93224-85-2 Well-known Company Product Price

  • Brand
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  • Alfa Aesar

  • (H32269)  2-Bromo-6-chlorobenzoic acid, 98%   

  • 93224-85-2

  • 1g

  • 559.0CNY

  • Detail
  • Alfa Aesar

  • (H32269)  2-Bromo-6-chlorobenzoic acid, 98%   

  • 93224-85-2

  • 5g

  • 1862.0CNY

  • Detail

93224-85-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromo-6-chlorobenzoic acid

1.2 Other means of identification

Product number -
Other names 2-bromo-6-chloro-benzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:93224-85-2 SDS

93224-85-2Relevant articles and documents

Synthesis of pyrrolnitrin and related halogenated phenylpyrroles

Morrison, Matthew D.,Hanthorn, Jason J.,Pratt, Derek A.

supporting information; experimental part, p. 1051 - 1054 (2009/07/18)

A general approach to halogenated arylpyrroles, including the antifungal natural product pyrrolnitrin, is described using newly synthesized halogenated pyrroles and 2,6-disubstituted nitrobenzenes or 2,6-disubstituted anilines.

RENIN INHIBITORS

-

Page/Page column 117, (2008/12/04)

Described are compounds which bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof.

RENIN INHIBITORS

-

Page/Page column 108, (2008/12/04)

Disclosed are compounds of Formula (I) wherein the R, R1, R2, R3, X, Y, A, Q, E, and G are defined herein. These compounds bind to aspartic proteases to inhibit their activity and are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also disclosed are methods of use of the compounds of Formula I for ameliorating or treating aspartic protease related disorders in a subject in need thereof.

Regioselective halogen-metal exchange reaction of 3-substituted 1,2-dibromo arenes: The synthesis of 2-substituted 5-bromobenzoic acids

Menzel, Karsten,Dimichele, Lisa,Mills, Paul,Frantz, Doug E.,Nelson, Todd D.,Kress, Michael H.

, p. 1948 - 1952 (2008/02/08)

Regioselective halogen-metal exchange reactions using isopropylmagnesium chloride were carried out on 3-substituted 1,2-dibromo arenes. Eleven examples are given. Georg Thieme Verlag Stuttgart.

Halogen-metal exchange of 3-substituted 1,2-dibromoarenes: The use of long-range JCH coupling constants to determine regiochemistry

DiMichele, Lisa,Menzel, Karsten,Mills, Paul,Frantz, Doug,Nelson, Todd

, p. 1041 - 1043 (2008/02/05)

Regioselective halogen/metal exchange reactions were carried out on a series of 3-substituted-1,2-dibromoarenes. Product mixtures were quenched with CO2 to form the corresponding benzoic acid analogs to facilitate HPLC and NMR analysis. Substitution at the 3-position could readily be assigned on the basis of 2D HMBC long-range correlations, while assignment at the 2-position was not as straightforward. The use of three-bond JCH coupling constant measurements, extracted from 1-D 1H coupled 13C experiments, were necessary to render unequivocal regio assignments. Copyright

Ortholithiation of unprotected benzoic acids: Application for novel 2-chloro-6-substituted benzoic acid syntheses

Gohier, Frederic,Castanet, Anne-Sophie,Mortier, Jacques

, p. 799 - 806 (2007/10/03)

2-Chloro-6-substituted benzoic acids of the type 2a-h were prepared by the tandem metallation sequence from 2-chlorobenzoic acid 1 with the 1:1 complex secbutyllithium/TMEDA in THF at -78°C followed by quenching with electrophiles.

Process development and pilot plant synthesis of methyl 2-bromo-6-chlorobenzoate

Hickey, Matthew R.,Allwein, Shawn P.,Nelson, Todd D.,Kress, Michael H.,Sudah, Osama S.,Moment, Aaron J.,Rodgers, Stephen D.,Kaba, Mahmoud,Fernandez, Paul

, p. 764 - 767 (2012/12/26)

A scalable process for a pilot plant synthesis of methyl 2-bromo-6-chlorobenzoate (1) is described. The strategy employed for the synthesis hinged on the esterification of the sterically encumbered parent acid produced through an o-lithiation/ carboxylati

NOVEL PHENYLALANINE DERIVATIVE

-

Page 74, (2008/06/13)

The present invention relates to the following phenylalanine derivatives or analogues thereof having an antagonistic activity to α4 integrin and therapeutic agents for various diseases concerning α4 integrin.

N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives

-

, (2008/06/13)

N-Biphenyl(substituted methyl)aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.

New phenylalanine derivatives

-

, (2008/06/13)

Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin.

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