93919-01-8

Basic information

• Product Name: 2-isopropyl-5-methylcyclohexyl stearate
• Synonyms: 2-isopropyl-5-methylcyclohexyl stearate;2-Isopropyl-5-methylcyclohexanol octadecanoate;5-Methyl-2-(1-methylethyl)cyclohexanol octadecanoate;Menthol octadecanoate
• CAS NO: 93919-01-8
• Molecular Formula: C₂₈H₅₄O₂
• Molecular Weight: 422.72716
• EINECS: 299-983-9
• Mol File: 93919-01-8.mol

Chemical Properties

• Boiling Point: 449.6°Cat760mmHg
• Flash Point: 255.3°C
• Appearance: /
• Density: 0.89g/cm³
• Vapor Pressure: 2.83E-08mmHg at 25°C
• Refractive Index: 1.466
• CAS DataBase Reference: 2-isopropyl-5-methylcyclohexyl stearate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-isopropyl-5-methylcyclohexyl stearate(93919-01-8)
• EPA Substance Registry System: 2-isopropyl-5-methylcyclohexyl stearate(93919-01-8)

Safety Data

• Hazardous Substances Data: 93919-01-8(Hazardous Substances Data)

Usage

Uses

Menthyl Stearate can be used as a transdermal path with hood transdermal effect and low cost

InChI:InChI=1/C28H54O2/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-27(24(2)3)28(29)30-26-21-19-20-25(4)23-26/h24-27H,5-23H2,1-4H3

Upstream product

• 2216-51-5 (-)-menthol 
• 57-11-4 stearic acid 
• 112-76-5 Stearoyl chloride 
• 822-16-2 sodium stearate 
• 10458-14-7 (2R,5S)-menthone 
• 638-08-4 stearic anhydride 

Downstream Products

• 5113-93-9 (1R)-trans-p-menth-2-ene 
• 619-52-3 (1R)-menth-3-ene 

Relevant articles and documents

Esterification of carboxylic acids with alcohols under microwave irradiation in the presence of zinc triflatet

The esterification of aliphatic and aromatic carboxylic acids with various alcohols (1°, 2°, 3°, benzylic) was studied under microwave irradiation in the presence of zinc triflate as catalyst; the reaction times were short and the yield of reactions was good to excellent.

Enzymatic esterification of (-)-menthol with fatty acids in solvent by a commercial lipase from Candida rugosa

Esterification of (-)-menthol with fatty acids in isooctane was successfully catalyzed using a commercial lipase, Lipase AY 'Amano' 30 from Candida rugosa in original powder form. The esterification reactions were performed to elucidate the effects of temperature, enzyme load, molar ratio of (-)-menthol/fatty acid, and fatty acid type, keeping the (-)-menthol concentration at 200 mM. At the optimal conditions for (-)-menthol esterification, determined at a (-)-menthol/lauric acid molar ratio of 1:1 and 35°C [1.5 g enzyme/g (-)-menthol, 0.1 g molecular sieves], the molar conversion of (-)-menthol after 48 h reached 93%. After 24 h, the lowest and the highest molar conversions of fatty acids at 2:1 molar ratio were obtained with myristic acid (71%) and margaric acid (98%), respectively. After 48 h, the molar conversions of lauric acid at molar ratios 2:1, 1:1, and 1:2 were 98, 93, and 49%, respectively.

Catalytic esterification of alcohols, carboxylic acids and transesterification reactions with cerium(IV) triflate

Esterification reactions of alcohols with acetic, chloroacetic, trifluoroacetic, propionic, stearic, and benzoic acids were catalyzed with Ce(OTf)4 in a solvent or under solvent-free conditions with high yields. The formylation and acetylation of primary and secondary alcohols were also easily achieved in ethyl formate and ethyl acetate. A high retention of the configuration was observed in the acetylation and formylation of (-)-menthol.