95477-52-4Relevant articles and documents
THE CHEMISTRY OF THE 6β-THIOAMIDOPENAM 1β-SULFOXIDES. THE 1,2,4-DITHIAZINEAZETIDINONES AND THIAZOLINEAZETIDINONES
Micetich, Ronald G.,Singh, Rajeshwar,Tetteh, Daniel M.,Morin, Robert B.
, p. 1617 - 1628 (2007/10/02)
6β-Thioamidopenam 1β-sulfoxides on thermolysis gave methyl 2-(3-substituted 4,5-dithia-2,7-diazabicyclooct-2-en-8-one-7-yl)-3-methyl-but-3-enoate (1,2,4-dithiazineazetidinones).The reaction of these compounds with halogenating agents is discussed.
THE CHLORINOLYSIS OF AZETIDINONE DISULFIDES
Micetich, Ronald G.,Singh, Rajeshwar,Merlo, Werner O.,Tetteh, Daniel M.,Shaw, Chia-Cheng,Morin, Robert M.
, p. 2757 - 2763 (2007/10/02)
The chlorinolysis of dithiazeneazetidinones, unsym-azetidinone disulfides, and 2-chloromethylpenams, with sulfuryl chloride produce the 2--3-chloromethyl-3-chlorosulfenylbutyric acid ester isomers in which the S-isomer predominates.Treatment of this compound (R and S isomers) with pyridine results in elimination of HSCl and formation of the Z and E isomers in which the Z isomer predominates.