95477-52-4

Basic information

• Product Name: methyl 2-<2'(R and S)-chloro-4'-oxo-3'S-α-phenoxy-α-chloromethyleneiminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate
• CAS NO: 95477-52-4
• Molecular Weight: 474.192
• Mol File: 95477-52-4.mol

Chemical Properties

• CAS DataBase Reference: methyl 2-<2'(R and S)-chloro-4'-oxo-3'S-α-phenoxy-α-chloromethyleneiminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-<2'(R and S)-chloro-4'-oxo-3'S-α-phenoxy-α-chloromethyleneiminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate(95477-52-4)
• EPA Substance Registry System: methyl 2-<2'(R and S)-chloro-4'-oxo-3'S-α-phenoxy-α-chloromethyleneiminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate(95477-52-4)

Safety Data

• Hazardous Substances Data: 95477-52-4(Hazardous Substances Data)

Upstream product

• 59997-09-0 methyl 3-phenoxy-4,5-dithia-2,7-diazabicyclo<4.2.0>oct-2-ene-8-one-7-isopropenyl acetate 

Downstream Products

• 67830-37-9 (R)-3-Methyl-2-((1R,5R)-7-oxo-3-phenoxy-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-but-3-enoic acid methyl ester 
• 62310-47-8 (Z)-4-Chloro-2-[(R)-2-chloro-3-(3,3-dimethyl-2-phenyl-isoureido)-4-oxo-azetidin-1-yl]-3-methyl-but-2-enoic acid methyl ester 
• 95477-53-5 methyl-2-<2'R-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate 
• 95477-53-5 methyl-2-<2'S-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate 
• 62310-51-4 (Z)-4-Chloro-2-((R)-2-chloro-4-oxo-3-phenoxycarbonylamino-azetidin-1-yl)-3-methyl-but-2-enoic acid methyl ester 
• 131713-44-5 (S)-((S)-2-Methyl-thiiranyl)-((1R,5R)-7-oxo-3-phenoxy-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-acetic acid methyl ester 

Relevant articles and documents

THE CHEMISTRY OF THE 6β-THIOAMIDOPENAM 1β-SULFOXIDES. THE 1,2,4-DITHIAZINEAZETIDINONES AND THIAZOLINEAZETIDINONES

6β-Thioamidopenam 1β-sulfoxides on thermolysis gave methyl 2-(3-substituted 4,5-dithia-2,7-diazabicyclooct-2-en-8-one-7-yl)-3-methyl-but-3-enoate (1,2,4-dithiazineazetidinones).The reaction of these compounds with halogenating agents is discussed.

THE CHLORINOLYSIS OF AZETIDINONE DISULFIDES

The chlorinolysis of dithiazeneazetidinones, unsym-azetidinone disulfides, and 2-chloromethylpenams, with sulfuryl chloride produce the 2--3-chloromethyl-3-chlorosulfenylbutyric acid ester isomers in which the S-isomer predominates.Treatment of this compound (R and S isomers) with pyridine results in elimination of HSCl and formation of the Z and E isomers in which the Z isomer predominates.