100379-00-8

Basic information

• Product Name: 2,6-Dimethylphenylboronic acid
• Synonyms: 2,6-DIMETHYLPHENYLBORONIC ACID;2,6-DIMETHYLBENZENEBORONIC ACID;AKOS BRN-0223;RARECHEM AH PB 0195;2,6-Dimethylphenylboronic;2,6-Dimethylbenzeneboronic acid 97%;2,6-Dimethylphenylboronic Acid (contains varying amounts of Anhydride);m-Xylene-2-boronic Acid
• CAS NO: 100379-00-8
• Molecular Formula: C₈H₁₁BO₂
• Molecular Weight: 149.98
• Product Categories: blocks;BoronicAcids;Aryl;Organoborons;B (Classes of Boron Compounds);Boronic Acids;Boronic acid;Boronic Acids;Boronic Acids and Derivatives;6
• Mol File: 100379-00-8.mol
• Article Data: 16

Chemical Properties

• Melting Point: 105 °C (dec.)(lit.)
• Boiling Point: 299.9 °C at 760 mmHg
• Flash Point: 135.2 °C
• Appearance: White/Crystalline Powder
• Density: 1.07 g/cm³
• Vapor Pressure: 0.000838mmHg at 25°C
• Refractive Index: 1.523
• Storage Temp.: 0-6°C
• Solubility: Soluble in methanol.
• PKA: 8.68±0.58(Predicted)
• CAS DataBase Reference: 2,6-Dimethylphenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethylphenylboronic acid(100379-00-8)
• EPA Substance Registry System: 2,6-Dimethylphenylboronic acid(100379-00-8)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 36/37/38-22
• Safety Statements: 37/39-26-36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 100379-00-8(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

Uses

Different sources of media describe the Uses of 100379-00-8 differently. You can refer to the following data:
1. suzuki reaction
2. It is used as a reagent for palladium catalyzed Suzuki-Miyaura coupling reactions, Pd-catalyzed homocouplings, Rhodium(I)-catalyzed 1,4-addition reactions. It is used in the preparation of protein kinase inhibitors, G Protein-Coupled Receptor.

InChI:InChI=1/C8H11BO2/c1-6-3-4-8(9(10)11)7(2)5-6/h3-5,10-11H,1-2H3

Upstream product

• 7732-18-5 water 
• 13675-18-8 tetrahydroxydiboron 
• 576-22-7 2-Bromo-m-xylene 
• 121-43-7 Trimethyl borate 
• 6781-98-2 2,6-dimethyl-1-chlorobenzene 
• 21450-64-6 (2,6-dimethylphenyl)magnesium bromide 
• 139719-91-8 dimethoxy(2,6-dimethylphenyl)borone 

Downstream Products

• 486397-33-5 3-(2,6-dimethyl-phenyl)-cyclohexanone 
• 30166-78-0 trans-1-(2,6-Dimethylphenyl)-2-benzolsulfonylethen 
• 902745-36-2 6-(2,6-dimethylphenyl)-pyridin-3-ylamine 
• 934470-91-4 1-tert-butyl 2-methyl (2S)-4-(2,6-dimethylphenyl)-2,5-dihydro-1H-pyrrole-1,2-dicarboxylate 
• 691905-26-7 2',6'-dimethyl-[1,1'-biphenyl]-3-carbaldehyde 
• 1021953-04-7 C₂₂H₂₀N₂O₂ 
• 1166397-96-1 2-(2,6-dimethylphenyl)-9H-xanthen-9-one 
• 1187733-97-6 3-chloro-5-(2,6-dimethylphenyl)isothiazole-4-carbonitrile 
• 1195785-09-1 4-(2,6-dimethylphenyl)indole 
• 944453-08-1 9-(2,6-dimethylphenyl)acridine 
• 1067883-66-2 (2',6'-dimethylbiphenyl-4-yl)phenyl-methanone 
• 105337-15-3 ethyl 2-(2,6-dimethylphenyl)acetate 

Relevant articles and documents

Concave reagents+. New 2′-substituted m-terphenyls

New 2′-substituted 2,2″,6,6″-tetramethyl-1,1′: 3′,1″-terphenyls have been synthesized. Solubility of concave acids 4b-6b could be enhanced by substitution in 4 and 4″ position, allowing the study of hydrogen-bonded heterodimers. Concave acids show larger

Photophysical properties of structural isomers of homoleptic Ir-complexes derived from xylenyl-substituted N-heterocyclic carbene ligands

The phosphorescence properties of fac-Ir(pmp)3, mer-Ir(pmp)3, fac-Ir(dmpmp)3 and mer-Ir(dmpmp)3 (where pmp = 3-methyl-1-phenyl-2,3-dihydro-1H-imidazo[4,5-b]pyridine and dmpmp = 1-(2′,6′-dimethylbiphenyl-2-yl)-3-

An efficient method for the hydrolysis of potassium organotrifluoroborates promoted by montmorillonite K10

An efficient and non-expensive method for conversion of diverse potassium organotrifluoroborates to their corresponding boronic acids promoted by montmorillonite K10 using water as the reaction solvent is described. Further interconversion of potassium organotrifluoroborates to their corresponding boronic esters, via boronic acid intermediates was also successfully accomplished. The products were obtained in good yields, being the rate of hydrolysis influenced by the type of substituent present in the boronic acid.