10430-90-7

Basic information

• Product Name: 1-PIPERAZINECARBOXYLIC ACID
• Synonyms: 1-PIPERAZINECARBOXYLIC ACID;Piperazine-1-carboxylic acid
• CAS NO: 10430-90-7
• Molecular Formula: C₅H₁₀N₂O₂
• Molecular Weight: 130.15
• Mol File: 10430-90-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-PIPERAZINECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PIPERAZINECARBOXYLIC ACID(10430-90-7)
• EPA Substance Registry System: 1-PIPERAZINECARBOXYLIC ACID(10430-90-7)

Safety Data

• Hazardous Substances Data: 10430-90-7(Hazardous Substances Data)

Usage

Classification

Cyclic amine with a carboxylic acid functional group

Common uses

Synthesis of pharmaceuticals and agrochemicals, precursor in the preparation of piperazine derivatives

Biological activities of piperazine derivatives

Antitumor, antimicrobial, and antidepressant properties

Potential use

Treatment of Parkinson's disease (neuroprotective effects in animal models)

Physical properties

Colorless, crystalline, and soluble in water

Versatility

Convenient and versatile building block for the production of a wide range of chemical products

Upstream product

• 110-85-0 piperazine 
• 124-38-9 carbon dioxide 
• 15719-64-9 methylammonium carbonate 

Downstream Products

• 110-85-0 piperazine 
• 96-49-1 [1,3]-dioxolan-2-one 
• 108-32-7 1,2-propylene cyclic carbonate 

Relevant articles and documents

Highly efficient and selective formation of hydrogencarbonate in CO 2 absorption process using piperidine and piperazine derivatives

This investigation demonstrated that bicarbonate ions were selectively formed over carbamate in a CO2 absorption process using piperidine and piperazine derivatives based on 13CNMR. Piperidines with methyl or hydroxymethyl substituent at 2 position (PiP-Me and PiP-MeOH) and 2,5-dimethylpiperazine (DM-PiZ) generated the bicarbonate ions as main adducts in reaction with CO2. The absorptions of CO2 by those aqueous amines (PiP-Me and DM-PiZ) were faster than those of MEA (2-aminoethanol).

Process for the continuous production of basic cyclic optically active alpha - amino acids

PCT No. PCT/EP96/04073 Sec. 371 Date Mar. 24, 1998 Sec. 102(e) Date Mar. 24, 1998 PCT Filed Sep. 18, 1996 PCT Pub. No. WO97/12881 PCT Pub. Date Apr. 10, 1997The invention pertains to a process for the continuous production of basic cyclic optically active alpha -amino acids of general formula (I) by continuous racemate splitting via diastereomeric salt pairs with re-racemisation of the residual amino acid or amino acid derivative in the mother liquid with the aid of an optically active acid.