1056246-70-8

Basic information

• Product Name: 2-bromo-1-tetralone
• Synonyms: 2-bromo-1-tetralone
• CAS NO: 1056246-70-8
• Molecular Weight: 225.085
• Mol File: 1056246-70-8.mol
• Article Data: 72

Chemical Properties

• CAS DataBase Reference: 2-bromo-1-tetralone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1-tetralone(1056246-70-8)
• EPA Substance Registry System: 2-bromo-1-tetralone(1056246-70-8)

Safety Data

• Hazardous Substances Data: 1056246-70-8(Hazardous Substances Data)

Upstream product

• 64245-04-1 2-bromo-1-hydroxy-1,2,3,4-tetrahydronaphthalene 
• 128-08-5 N-Bromosuccinimide 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 447-53-0 1,2-Dihydronaphthalene 
• 51114-70-6 2,2-dibromo-1,2,3,4-tetrahydronaphthalen-1-one 
• 529-33-9 1,2,3,4-Tetrahydro-1-naphthol 
• 3333-24-2 4-bromo-1,2-dihydronaphthalene 
• 2018-87-3 1,2-dibromo-1,2,3,4-tetrahydro-naphthalene 
• 38858-72-9 1-trimethylsiloxy-3,4-dihydronaphthalene 
• 84716-82-5 4-methoxy-1,2-dihydronaphthalene 
• 19455-84-6 3,4-dihydronaphthalen-1-yl acetate 
• 71-43-2 benzene 
• 207398-88-7 1-benzyloxy-1,2,3,4-tetrahydro-naphthalene 

Downstream Products

• 90-15-3 α-naphthol 
• 64559-97-3 2-hydroxy-1-tetralone 
• 119275-95-5 cyclohexyl-(1-cyclohexyl-4,5-dihydro-1H-naphtho[1,2-d]thiazol-2-yliden)-amine 
• 129632-82-2 3-Methoxy-4-methyl-benzoic acid 1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl ester 
• 20841-46-7 2-(phenylthio)-3,4-dihydronaphthalen-1(2H)-one 
• 120981-86-4 2-(5-Hydroxymethyl-3-phenyl-[1,2,4]triazol-1-yl)-3,4-dihydro-2H-naphthalen-1-one 
• 776-79-4 2-(2-carboxyethyl)benzoic acid 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 562069-24-3 1-oxo-1,2,3,4-tetrahydro-2-naphthalenyl-2-(4-methylsulfanylphenyl)acetate 
• 503174-37-6 3a-hydroxy-1-(4-methylsulfanyl-phenyl)-4,5-dihydro-3aH-naphtho[2,1-b]furan-2-one 
• 521917-51-1 (3,4-dihydronaphthalen-2-yl)boronic acid 
• 1011794-37-8 1-(p-tolyl)-2-benzoylimino-4,5-dihydro-1H-naphtho[1,2-d]thiazole 
• 1345728-95-1 2-phenyl-4,5-dihydronaphtho[2,1-b]furan 
• 112108-01-7 ecopipam 

Relevant articles and documents

Acridine Orange Hemi(Zinc Chloride) Salt as a Lewis Acid-Photoredox Hybrid Catalyst for the Generation of α-Carbonyl Radicals

A readily accessible organic-inorganic hybrid catalyst is reported for the reductive fragmentation of α-halocarbonyl compounds. The robust hybrid catalyst is a self-stabilizing combination of ZnCl2 Lewis acid and acridine orange as the photoactive organic dye. Mechanistic specifics of this hybrid catalyst have been studied in detail using both photophysical and electrochemical experiments. A systematic study enabled the discovery of the appropriate Lewis acid for the effective LUMO stabilization of α-halocarbonyl compounds and thereby lowering of reduction potential within the range of a standard organic dye. This strategy resolves the issues like dehalogenative hydrogenation or homo-coupling of alkyl radicals by guiding the photoredox cycle through an oxidative quenching pathway. The cooperativity between the photoactive organic dye and the Lewis acid counterparts empowers functionalization with a wide range of coupling partners through efficient and controlled generation of alkyl radicals and serves as an appropriate alternative to the expensive late transition metal-based photocatalysts. To demonstrate the application potential of this cooperative catalytic system, four different synthetic transformations of α-carbonyl bromides were explored with broad substrate scopes.

Annulation reaction of cyclic pyridinium ylides with: In situ generated azoalkenes for the construction of spirocyclic skeletons

Two new types of cyclic pyridinium ylides were designed and further used in reactions with azoalkenes to access structurally diverse spirocyclic compounds. A range of spiropyrazoline oxindoles could be smoothly obtained in up to 99% yield via a [4 + 1] annulation process with oxindole 3-pyridinium ylides as C1 synthons. Similarly, a series of spiropyrazoline indanones could be prepared with indanone 2-pyridinium ylides as C1 synthons. This work represents the first example of cyclic pyridinium ylides as C1 synthons for the efficient construction of spirocyclic compounds.

A Method for the Catalytic Enantioselective Synthesis of Chiral α-Azido and α-Amino Ketones from Racemic α-Bromo Ketones, and Its Generalization to the Formation of Bonds to C, O, and S

A new and practical method has been developed for the transformation of racemic α-bromo ketones to chiral α-azido and α-amino ketones with high enantioselectivity using phase transfer, ion-pair mediated reactions with a recoverable chiral quaternary salt (10 mol %) as catalyst in fluorobenzene-water. The process has been generalized to a variety of other attachments including of C, O, S, and NHR.