105705-31-5Relevant articles and documents
NOVEL HETEROCYCLIC COMPOUNDS AS HSP90-INHIBITORS
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Page/Page column 325, (2008/06/13)
Novel heterocyclic compounds are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agent. Method of synthesis and use of such compounds are also described.
Practical and regioselective brominations of aromatic compounds using tetrabutylammonium peroxydisulfate
Park, Min Young,Yang, Seung Gak,Jadhav, Vidyadhar,Kim, Yong Hae
, p. 4887 - 4890 (2007/10/03)
Direct bromination of wide range of aromatic compounds substituted with electron donating groups such as methoxy, hydroxy, or amino groups have been achieved with high regioselectivity by the reaction with Br2 in the presence of tetrabutylammonium peroxydisulfate 1 under mild conditions in acetonitrile in excellent yields. The use of lithium bromide as a bromination reagent afforded high yields of monobromo compounds with complete regioselectivity under neutral and mild reaction conditions in acetonitrile.