110567-21-0Relevant articles and documents
PCSK9 INHIBITORS AND METHODS OF USE THEREOF
-
, (2020/07/31)
The invention relates to novel heteroaryl compounds and pharmaceutical preparations thereof. The invention further relates to methods of treating or preventing cardiovascular diseases, and methods treating sepsis or septic shock, using the novel heterocyclic compounds disclosed herein.
STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING
-
, (2019/05/30)
The present disclosure provides STING modulators/agonists, and methods of synthesis and methods for using for the prophylaxis or treatment of cancer and other STING-related diseases. The present disclosure relates to a compound represented by the Formula (I): wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.
The synthesis of possible transition state analogue inhibitors of thymidine phosphorylase
Evans, Gary B.,Gainsford, Graeme J.,Schramm, Vern L.,Tyler, Peter C.
, p. 406 - 409 (2015/04/27)
The synthetically challenging SN2 transition state mimic for thymidine phosphorylase, along with its phosphonate analogue, were synthesised via a modified Corey-Link reaction in good overall yields and ensuring the correct stereochemical outcome.