668996-17-6Relevant articles and documents
ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A
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, (2016/04/20)
Enantiomers of 1',6'-isoneplanocin, including derivatives of the enantiomers of 1',6'-isoneplanocin, are disclosed along with novel synthetic methods. In particular, a substituted cyclopentane epoxide is synthesized into the enantiomers of 1',6'-isoneplan
Novel 3′-deoxy analogs of the anti-HBV agent entecavir: Synthesis of enantiomers from a single chiral epoxide
Ruediger, Edward,Martel, Alain,Meanwell, Nicholas,Solomon, Carola,Turmel, Brigitte
, p. 739 - 742 (2007/10/03)
A synthesis of novel 3′-deoxy analogs of the anti-HBV agent entecavir (BMS-200475) was devised using regioselective ring opening of suitable cyclopentene epoxides as the key step. This versatile approach afforded access to an enantiomeric pair of carbocyclic nucleosides from a single chiral intermediate.
