110623-24-0

Basic information

• Product Name: 5-(4-chlorophenyl)-2,4-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
• Synonyms: 3H-1,2,4-triazole-3-thione, 5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-
• CAS NO: 110623-24-0
• Molecular Formula: C₁₀H₁₀ClN₃S
• Molecular Weight: 239.7245
• Mol File: 110623-24-0.mol

Chemical Properties

• Boiling Point: 302.1°C at 760 mmHg
• Flash Point: 136.5°C
• Density: 1.33g/cm³
• Vapor Pressure: 0.00101mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: 5-(4-chlorophenyl)-2,4-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-chlorophenyl)-2,4-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(110623-24-0)
• EPA Substance Registry System: 5-(4-chlorophenyl)-2,4-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(110623-24-0)

Safety Data

• Hazardous Substances Data: 110623-24-0(Hazardous Substances Data)

Usage

Class

1,2,4-triazole derivatives

Functional Groups

Thione (-S), Chlorophenyl (4-chlorophenyl)

Applications

Medicinal chemistry, drug discovery, and development

Potential Pharmaceutical Properties

Antifungal, antibacterial, antioxidant, anti-inflammatory, antidiabetic

Structure

Consists of a 1,2,4-triazole ring with a thione functional group and a 4-chlorophenyl group attached

Upstream product

• 110623-43-3 1-(4-chlorobenzoyl)-2,4-dimethylthiosemicarbazide 
• 144-55-8 sodium hydrogencarbonate 
• 13121-76-1 bis(tricyclohexyltin)sulfide 
• 60-29-7 diethyl ether 
• 116114-13-7 5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3H-1,2,4-triazol-3-one 
• 122-01-0 4-chloro-benzoyl chloride 

Relevant articles and documents

5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones useful as antidepressants

This invention relates to novel 5-(Rn -phenyl)-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and to their use as antidepressants.

Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione

This invention relates to a novel method for the treatment of hemorrhagic and thrombotic thrombocytosis by means of administration of a 5-(4-chlorophenyl)-2,4-dimethyl-3H-1,2,4-triazole-3-thione.

5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants

This invention relates to novel 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones, to the intermediates and processes for their preparation, and to their use as antidepressants.

2,4-Dihydro-3H-1,2,4-triazole-3-thiones as Potential Antidepressant Agents

A series of 5-aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones was prepared and evaluated for potential antidepressant activity.Members of this series were generally prepared by the alkaline ring closures of the corresponding 1-aroylthiosemicarbazides.Several

The Bis(tricyclohexylstannyl) Sulfide Thionation of 3H-1,2,4-Triazol-3-ones

5-Aryl-2,4-dialkyl-2,4-dihydro-3H-1,2,4-triazol-3-ones may be converted in 55-74percent yield to the corresponding 3H-1,2,4-triazole-3-thiones by using the combination bis(tricyclohexylstannyl) sulfide/boron trichloride.