115186-31-7 Usage
Uses
Used in Pharmaceutical Industry:
N-Boc-N'-Fmoc-D-lysine is used as a building block for the synthesis of various pharmaceutical compounds. Its application is primarily due to its ability to be incorporated into the structure of complex molecules, contributing to the development of novel drugs with potential therapeutic benefits.
Used in Organic Chemistry:
In the realm of organic chemistry, N-Boc-N'-Fmoc-D-lysine is used as a reagent for the synthesis of aza-amino acids. Aza-amino acids are non-natural amino acids that possess a nitrogen atom in their side chain, which can be crucial for the development of new chemical entities with unique properties and applications.
Used in Peptide Synthesis:
N-Boc-N'-Fmoc-D-lysine is also employed in the synthesis of peptides, which are short chains of amino acids linked by peptide bonds. The compound's protected structure allows for the stepwise assembly of peptide chains, facilitating the creation of complex peptide-based drugs and bioactive molecules.
Used in Research and Development:
Due to its unique structural features, N-Boc-N'-Fmoc-D-lysine is often used in research and development for the exploration of new chemical reactions and the design of novel molecular structures. Its application in this field aids in the advancement of scientific knowledge and the discovery of innovative solutions in various industries, including pharmaceuticals, materials science, and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 115186-31-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,1,8 and 6 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 115186-31:
(8*1)+(7*1)+(6*5)+(5*1)+(4*8)+(3*6)+(2*3)+(1*1)=107
107 % 10 = 7
So 115186-31-7 is a valid CAS Registry Number.
InChI:InChI=1/C26H32N2O6/c1-26(2,3)34-25(32)28-22(23(29)30)14-8-9-15-27-24(31)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m1/s1
115186-31-7Relevant articles and documents
Solution phase synthesis of β-peptides using micro reactors
Watts, Paul,Wiles, Charlotte,Haswell, Stephen J,Pombo-Villar, Esteban
, p. 5427 - 5439 (2007/10/03)
The synthesis of β-peptides has been successfully performed using a borosilicate glass micro reactor, in which a network of channels has been produced using a photolithographic and wet etching method. The reagents were mobilised by electroosmotic flow (EOF). The micro reactor was initially evaluated using a carbodiimide coupling reaction to form a dipeptide. The methodology has been extended such that the peptides may also be produced via the pentafluorophenyl ester derivatives of amino acids. It was found that performing the pentafluorophenyl ester reactions in the micro reactor resulted in an increase in the reaction efficiency over the traditional batch method. We postulate that the enhancement in rate of reaction is an electrochemical phenomenon, due to the reaction being performed in an electric field, which is unique to micro reactor systems. It has also been demonstrated that selective deprotection of the resultant dipeptides can be achieved. This approach has been used in the synthesis of a tripeptide.
Solid-Phase Total Synthesis of Oscillamide Y and Analogues
Marsh, Ian R.,Bradley, Mark,Teague, Simon J.
, p. 6199 - 6203 (2007/10/03)
We report an efficient solid phase synthesis of oscillamide Y and three analogues. The cyclic peptide was prepared using a combination of Fmoc and allyl chemistries and an acid labile Wang type linker. The urea functionality was smoothly incorporated usin