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1180843-77-9

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1180843-77-9 Usage

Uses

Used in Pharmaceutical Industry:
1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one, 11-chloro-2,3,3a,12b-tetrahydro-2-Methylis used as a potential pharmaceutical agent for [specific medical application or drug development] because of [reason related to its chemical properties or potential therapeutic effects].
Used in Agrochemical Industry:
In the agrochemical field, 1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one, 11-chloro-2,3,3a,12b-tetrahydro-2-Methylis used as a [specific agrochemical application, such as a pesticide or herbicide] for [reason related to its chemical properties that make it effective in this context].
Used in Materials Science:
1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one, 11-chloro-2,3,3a,12b-tetrahydro-2-Methylis utilized in materials science as a [specific material or component] for [reason related to its unique structural features that contribute to the desired material properties].

Check Digit Verification of cas no

The CAS Registry Mumber 1180843-77-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,0,8,4 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1180843-77:
(9*1)+(8*1)+(7*8)+(6*0)+(5*8)+(4*4)+(3*3)+(2*7)+(1*7)=159
159 % 10 = 9
So 1180843-77-9 is a valid CAS Registry Number.

1180843-77-9Relevant articles and documents

Preparation method of asenapine intermediate

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Paragraph 0027; 0035-0037; 0038; 0041, (2021/08/21)

The invention discloses a preparation method of an asenapine intermediate and belongs to the technical field of synthesis of asenapine intermediates. In the ASP07 preparation process, iodine is added for an initiation reaction, the reaction temperature is controlled to be 40 DEG C or below, inorganic acid is used for neutralization after the reaction is finished, hydrochloric acid and sulfuric acid are preferentially selected, inorganic base is used for a ring-opening reaction in the ASP08 preparation process, potassium hydroxide and sodium hydroxide are preferentially selected, the reaction temperature is 80-90 DEG C, and in the process of preparing the asenapine intermediate, ethanol and methanol are used as refining solvents, so that a high-purity product can be obtained. The asenapine intermediate is mainly applied to atypical antipsychotic drugs.

PROCESS FOR THE PREPARATION OF ASENAPINE MALEATE

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Paragraph 0054, (2015/04/28)

The present invention provides a process for the preparation of asenapine maleate of Formula (I), comprising: intra-molecular cyclization of the intermediate of Formula (II) to obtain the intermediate of Formula (III) using aluminium halide.

PROCESS FOR THE PREPARATION OF ASENAPINE INTERMEDIATE

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Page/Page column 8; 9, (2013/06/27)

The present invention provides a process for the preparation of the asenapine intermediate of Formula (III) using a magnesium-methanol-acetic acid mixture.

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