118727-34-7

Basic information

• Product Name: 1,3,5-Tris(4-aminophenyl)benzene
• Synonyms: 1,3,5-Tris(4-aminophenyl)benzene;5'-(4-AMinophenyl)-[1,1':3',1''-terphenyl]-4,4''-diaMine;4-[3,5-bis(4-aminophenyl)phenyl]aniline
• CAS NO: 118727-34-7
• Molecular Formula: C₂₄H₂₁N₃
• Molecular Weight: 351.44364
• Mol File: 118727-34-7.mol

Chemical Properties

• Melting Point: >200℃ (ethanol )
• Boiling Point: 576.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.203±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Acetonitrile (Slightly), DMSO (Slightly, Heated)
• PKA: 4.94±0.10(Predicted)
• CAS DataBase Reference: 1,3,5-Tris(4-aminophenyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-Tris(4-aminophenyl)benzene(118727-34-7)
• EPA Substance Registry System: 1,3,5-Tris(4-aminophenyl)benzene(118727-34-7)

Safety Data

• Hazardous Substances Data: 118727-34-7(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
1,3,5-Tris(4-aminophenyl)benzene is used as a reagent for catalytic asymmetric synthesis, which is crucial for the production of chiral covalent compounds. These compounds are essential in the pharmaceutical industry, as they often exhibit different biological activities and are the basis for many drugs.
In the field of asymmetric synthesis, 1,3,5-Tris(4-aminophenyl)benzene plays a significant role in facilitating the selective formation of one enantiomer over another, leading to the creation of optically active compounds with desired properties. This selective synthesis is vital for ensuring the efficacy and safety of pharmaceutical products, as different enantiomers can have distinct biological effects.
Used in Pharmaceutical Industry:
1,3,5-Tris(4-aminophenyl)benzene is also used in the pharmaceutical industry for the development of novel drugs with improved chiral selectivity. The ability to control the stereochemistry of a compound is essential for creating drugs with targeted effects and reduced side effects. This reagent aids in the synthesis of such chiral drugs, contributing to the advancement of medical treatments.

Upstream product

• 29102-61-2 1,3,5-tris(4-nitrophenyl)benzene 
• 876593-24-7 1,3,5-tris{4-[N-(tert-butoxycarbonyl)amino]phenyl}benzene 
• 100-19-6 (4-nitrophenyl)ethanone 
• 626-39-1 1,3,5-trisbromobenzene 
• 380430-49-9 [4-(tert-butoxycarbonylamino)phenyl]boronic acid 
• 99-92-3 p-aminobenzophenone 
• 89415-43-0 (4-aminophenyl)boronic acid 
• 14235-81-5 4-Ethynylaniline 
• 555-16-8 4-nitrobenzaldehdye 
• 214360-73-3 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline 
• 106-40-1 4-bromo-aniline 
• 89641-21-4 benzene-1,3,5-triyltriboronic acid 
• 101-80-4 4,4'-oxydiphenylene diamine 
• 102852-92-6 1,3,5-tris(4'-aminophenyloxy)benzene 

Downstream Products

• 612-71-5 1,3,5-triphenylbenzene 
• 343239-58-7 5′-phenyl-[1,1′:3′,1″-terphenyl]-4-amine 
• 894428-16-1 1,3,5-tris(4-octyloxybenzoylamino)phenylbenzene 
• 894428-17-2 1,3,5-tris(4-dodecyloxybenzoylamino)phenylbenzene 
• 894428-18-3 1,3,5-tris(4-cetyloxybenzoylamino)phenylbenzene 
• 894428-23-0 1,3,5-tris(3,4,5-tridodecyloxybenzoylamino)phenylbenzene 
• 929694-13-3 1,3,5-tris(3,4,5-tricetyloxybenzoylamino)phenylbenzene 
• 1050504-04-5 C₄₅H₄₂B₃N₃O₆ 

Relevant articles and documents

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