1224-93-7

Basic information

• Product Name: (5β)-androstan-3ξ-ol
• CAS NO: 1224-93-7
• Molecular Weight: 276.462
• Mol File: 1224-93-7.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: (5β)-androstan-3ξ-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (5β)-androstan-3ξ-ol(1224-93-7)
• EPA Substance Registry System: (5β)-androstan-3ξ-ol(1224-93-7)

Safety Data

• Hazardous Substances Data: 1224-93-7(Hazardous Substances Data)

Upstream product

• 481-29-8 Epiandrosterone 
• 7148-51-8 5α-androst-16-en-3β-ol 
• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 201230-82-2 carbon monoxide 
• 96-20-8 2-aminobutanol 
• 16369-21-4 N-(2-hydroxyethyl)-N-propylamine 
• 156-87-6 propan-1-ol-3-amine 
• 4732-78-9 (3β,5α,13β)-3-hydroxy-18-norandrostan-17-one 
• 1254-34-8 3β-tosyloxy-5α-androstane 
• 1254-34-8 3α-tosyloxy-5α-androstane 
• 396079-66-6 17α-benzoyloxy-5β-androstanone-(3) 
• 52225-35-1 5β-androst-16-en-3-one 
• 36025-82-8 3-oxoandrost-4-en-17α-yl benzoate 
• 4572-71-8 (3α,5β)-3-hydroxyandrost-16-ene 

Downstream Products

• 1225-48-5 5α-Androstan-2-on 
• 230630-67-8 P¹,P²-bis(benzyl 5α-androstan-3β-yl) pyrophosphate 
• 230630-64-5 benzyl hydrogen 5α-androstan-3β-yl phosphate 
• 1224-95-9 androstan-3-one 
• 1043-16-9 2.3-seco-5α-androstanedioic acid-(2.3) 
• 230630-63-4 dibenzyl 5α-androstan-3β-yl phosphate 
• 1254-34-8 5α-Androstan-3β-ol-tosylat 
• 18069-68-6 5β-androstan-3-one 

Relevant articles and documents

Nickel-Catalyzed Intramolecular Decarbonylative Coupling of Aryl Selenol Esters

This report describes a method for Ni-catalyzed intramolecular decarbonylative coupling, which enables the conversion of areneselenol esters to diaryl selenides. The inexpensive and readily available catalyst can be employed under mild reaction conditions for the construction of structurally diverse diaryl selenides, including heterocyclic and natural product derivatives. (Figure presented.).

HUMAN GHRELIN O-ACYL TRANSFERASE INHIBITORS

A class of cyanosteroid compounds that efficiently inhibit ghrelin acylation by ghrelin O-acyltransferase. The compounds have a steroid scaffold with α,β-unsaturated ketone in the A ring position such an a-cyanoenone. Exemplary compounds include (5S,8S,9S,10S, 13S,14S)-10,13-dimethyl-3-oxo-4,5,6,7,8,9,10,11,12,13,14,15,16,17- tetradecahydro-3H-cyclopenta[a]phenanthrene-2-carbonitrile.

SHIP INHIBITION TO COMBAT OBESITY

The present invention relates to the use of SHIP1 inhibitors and pan-SHIP1/2 inhibitors in various methods, including, without limitation: (i) a method to treat obesity or reduce body fat of an obese subject; (ii) a method to limit bone development in a subject suffering from an osteopetrotic or sclerotic disease; (iii) a method to treat or prevent diabetes; (iv) a method to reduce glucose intolerance or insulin resistance; and (v) a method to lower cholesterol.