1227694-96-3 Usage
Description
(E)-N-(3-(3-(DiMethylaMino)acryloyl)phenyl)-N-ethylacetaMide is a chemical compound with a complex structure, characterized by its (E)-N-(3-(3-(DiMethylaMino)acryloyl)phenyl)-N-ethylacetaMide formula. It is a reactant utilized in the synthesis of impurities related to Zaleplon, a selective non-benzodiazepine GABAA receptor agonist.
Uses
Used in Pharmaceutical Industry:
(E)-N-(3-(3-(DiMethylaMino)acryloyl)phenyl)-N-ethylacetaMide is used as a reactant for the synthesis of impurities related to Zaleplon (Z145000), a selective non-benzodiazepine GABAA receptor agonist. This application is significant in the development and production of pharmaceuticals targeting the GABAA receptor, which plays a crucial role in reducing anxiety and promoting sleep.
In the context of Zaleplon synthesis, (E)-N-(3-(3-(DiMethylaMino)acryloyl)phenyl)-N-ethylacetaMide serves as an essential component in the production process, ensuring the creation of the desired compound with the intended therapeutic effects. Its role in the pharmaceutical industry highlights the importance of understanding and utilizing complex chemical structures for the development of novel medications and treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 1227694-96-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,6,9 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1227694-96:
(9*1)+(8*2)+(7*2)+(6*7)+(5*6)+(4*9)+(3*4)+(2*9)+(1*6)=183
183 % 10 = 3
So 1227694-96-3 is a valid CAS Registry Number.
1227694-96-3Relevant articles and documents
A new method for synthesizing zaleplon (by machine translation)
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, (2016/10/10)
The present invention provides a new method for synthesizing zaleplon. In particular, the method of the invention takes the acetophenone as raw materials, make N-ethyl-N-[ 3 - (3- dimethyl amine -1-oxo-2-propenyl) phenyl] acetamide, with 3-amino-4-cyano pyrazole reaction, forming N-[ 3 - (3-cyano-pyrazolo [1,5-α] pyrimidin-7-yl) phenyl]-N-ethyl acetamide. The synthetic route of the present invention of fewer steps, after treatment is simple, low cost, suitable for industrial production. (by machine translation)
PROCESS FOR THE PREPARATION OF ZALEPLON AND AN INTERMEDIATE THEREOF
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Page/Page column 9-10, (2008/06/13)
A process for the preparation of N-[3-[3-(dimethylamino)-l-oxo-2-propenyl]phenyl]-N-ethyl acetamide of formula (II), comprising reacting a compound N-[3-[3-(dimethylamino)-l-oxo-2-propenyl]phenyl] acetamide of formula (III), with an ethylating agent in th
